来自德国和奥地利的产中毒性休克综合征毒素-1（TSST-1）的金黄色葡萄球菌菌株的氨基酸需求。
Amino acid requirements of Staphylococcus aureus strains from Germany and Austria that produce toxic shock syndrome toxin-1 (TSST-1).
作者信息
Dickgiesser N, Eppli P
机构信息
Institut für Hygiene und Medizinische Mikrobiologie, Fakultät für Klinische Medizin, Mannheim der Universität Heidelberg.
出版信息
Zentralbl Bakteriol Mikrobiol Hyg A. 1988 Mar;268(1):1-7. doi: 10.1016/s0176-6724(88)80107-x.
Amino acid requirements of 156 toxic shock syndrome toxin-1 (TSST-1) producing Staphylococcus aureus strains from Germany and 37 strains from Austria have been determined. They were compared with TSST-1 negative S. aureus. Most of the strains required proline and valine with no significant differences between TSST-1 positive and negative S. aureus. There was no correlation between tryptophan auxotypy and TSST-1 producing strains. On complete chemically defined medium good bacterial growth was usually observed. Nevertheless, many strains stopped toxin production under these conditions. S. aureus strains with TSST-1 synthesis on complete medium required phenylalanine and cysteine for TSST-1 production mainly.
已测定来自德国的156株产中毒性休克综合征毒素-1（TSST-1）的金黄色葡萄球菌菌株和来自奥地利的37株菌株的氨基酸需求。将它们与TSST-1阴性的金黄色葡萄球菌进行了比较。大多数菌株需要脯氨酸和缬氨酸，TSST-1阳性和阴性的金黄色葡萄球菌之间无显著差异。色氨酸营养缺陷型与产TSST-1菌株之间没有相关性。在完全化学成分确定的培养基上通常观察到良好的细菌生长。然而，许多菌株在这些条件下停止产毒素。在完全培养基上合成TSST-1的金黄色葡萄球菌菌株主要需要苯丙氨酸和半胱氨酸来产生TSST-1。
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