Valle J, Vadillo S, Piriz S, Gomez-Lucia E
Unidad de Microbiologia e Inmunologia, Facultad de Veterinaria, Universidad de Extremadura, Caceres, Spain.
Appl Environ Microbiol. 1991 Mar;57(3):889-91. doi: 10.1128/aem.57.3.889-891.1991.
The ability of staphylococcal strains isolated from different anatomical sites in 133 healthy goats to produce toxic shock syndrome toxin 1 (TSST-1) and the presence of antibodies to this toxin in serum and milk were studied. The enzyme-linked immunosorbent assay method was used to detect both the toxin and the presence of antibodies. Of a total of 342 staphylococcal strains studied, 86 (25.2%) were found to produce TSST-1. Specific antibodies to TSST-1 were found in the serum of 57 (42.9%) of the animals studied and the milk of 63 (47.4%) of the animals. These results suggest that goats are frequently in contact with staphylococci that produce TSST-1, a toxin usually associated with Staphylococcus aureus strains isolated from cases of toxic shock syndrome in humans.
研究了从133只健康山羊不同解剖部位分离出的葡萄球菌菌株产生毒性休克综合征毒素1（TSST-1）的能力，以及血清和乳汁中针对该毒素抗体的存在情况。采用酶联免疫吸附测定法检测毒素和抗体的存在情况。在所研究的总共342株葡萄球菌菌株中，发现86株（25.2%）产生TSST-1。在所研究动物的血清中，57只（42.9%）检测到针对TSST-1的特异性抗体，在63只（47.4%）动物的乳汁中也检测到该抗体。这些结果表明，山羊经常接触产生TSST-1的葡萄球菌，这种毒素通常与从人类毒性休克综合征病例中分离出的金黄色葡萄球菌菌株有关。
