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免疫功能低下人群抗真菌管理的现状

The Current State of Antifungal Stewardship in Immunocompromised Populations.

作者信息

Alegria William, Patel Payal K

机构信息

Department of Quality, Patient Safety and Effectiveness, Stanford Health Care, 300 Pasteur Drive, Lane 134 L1C36, Stanford, CA 94305, USA.

Stanford Antimicrobial Safety and Sustainability Program, Stanford, CA 94305, USA.

出版信息

J Fungi (Basel). 2021 Apr 30;7(5):352. doi: 10.3390/jof7050352.

Abstract

Inappropriate antifungal use is prevalent and can lead to drug-resistant fungi, expose patients to adverse drug events, and increase healthcare costs. While antimicrobial stewardship programs have traditionally focused on antibiotic use, the need for targeted antifungal stewardship (AFS) intervention has garnered interest in recent years. Despite this, data on AFS in immunocompromised patient populations is limited. This paper will review the current state of AFS in this complex population and explore opportunities for multidisciplinary collaboration.

摘要

不恰当的抗真菌药物使用很普遍,可能导致耐药真菌产生,使患者面临药物不良事件,并增加医疗成本。虽然抗菌药物管理计划传统上侧重于抗生素的使用,但近年来,针对性抗真菌药物管理(AFS)干预的必要性已引起关注。尽管如此,关于免疫功能低下患者群体中AFS的数据仍然有限。本文将综述这一复杂人群中AFS的现状,并探讨多学科合作的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a0/8145600/e34c2a6f97e3/jof-07-00352-g001.jpg

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