Department of Biomedical Sciences, School of Biosciences and Technology, Vellore Institute of Technology, Vellore 632014, India.
Department of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 8891692, Japan.
Int J Mol Sci. 2021 Apr 29;22(9):4748. doi: 10.3390/ijms22094748.
Dermal wound healing describes the progressive repair and recalcitrant mechanism of 12 damaged skin, and eventually, reformatting and reshaping the skin. Many probiotics, nutritional supplements, metal nanoparticles, composites, skin constructs, polymers, and so forth have been associated with the improved healing process of wounds. The exact mechanism of material-cellular interaction is a point of immense importance, particularly in pathological conditions such as diabetes. Bioengineered alternative agents will likely continue to dominate the outpatient and perioperative management of chronic, recalcitrant wounds as new products continue to cut costs and improve the wound healing process. This review article provides an update on the various remedies with confirmed wound healing activities of metal-based nanoceutical adjuvanted agents and also other nano-based counterparts from previous experiments conducted by various researchers.
皮肤创伤愈合描述了受损皮肤的渐进式修复和顽固性机制，最终实现皮肤的重新格式化和重塑。许多益生菌、营养补充剂、金属纳米粒子、复合材料、皮肤构建物、聚合物等都与改善创伤愈合过程有关。材料-细胞相互作用的确切机制是一个非常重要的点，特别是在糖尿病等病理条件下。生物工程替代剂可能会继续主导慢性、顽固性创伤的门诊和围手术期管理，因为新产品继续降低成本并改善创伤愈合过程。本文综述了各种经证实具有金属纳米药物佐剂和其他纳米基对应物的创伤愈合活性的治疗方法，这些方法来自不同研究人员之前的实验。
