Klouth Eva, Zablotski Yury, Goehring Lutz S
Equine Hospital Center for Clinical Veterinary Medicine, Faculty of Veterinary Medicine Ludwig-Maximilians University, 80539 Munich, Germany.
Center for Clinical Veterinary Medicine, Faculty of Veterinary Medicine Ludwig-Maximilians University, 80539 Munich, Germany.
Pathogens. 2021 Apr 29;10(5):537. doi: 10.3390/pathogens10050537.
Equid herpesvirus type 1 (EHV-1) causes several outbreaks of abortion and/or equid herpesvirus-associated myeloencephalopathy (EHM) worldwide each year. EHM is of great concern, as permanent neurological gait anomalies can leave a horse unfit for future use. The study assesses the risk factors associated with the occurrence of EHM. During an unmitigated outbreak, 141 adult horses/ponies of several distinct breeds were evaluated-using multiple Bayesian logistic regression calculating the odds ratios for breed, age, and sex. In total, 33 of the 141 horses showed signs of EHM. Fjord horses and warmblood horses were overrepresented among those developing EHM. The pony breeds, Welsh and Shetland ponies, were underrepresented. In addition, age and sex were not associated with the risk for EHM. The main limitation was that it was a retrospective analysis with some flaws of documentation. It can be concluded that breed was a significant risk factor for developing EHM during this outbreak.
1型马疱疹病毒（EHV-1）每年在全球引发数次流产疫情和/或马疱疹病毒相关脊髓脑脊髓炎（EHM）疫情。EHM备受关注，因为永久性神经步态异常会使马匹无法继续用于未来用途。该研究评估了与EHM发生相关的风险因素。在一次未得到缓解的疫情期间，对141匹不同品种的成年马/小马驹进行了评估，使用多重贝叶斯逻辑回归计算品种、年龄和性别的比值比。141匹马中共有33匹出现了EHM症状。在患EHM的马匹中，峡湾马和温血马的占比过高。威尔士矮种马和设得兰矮种马这两个矮种马品种的占比过低。此外，年龄和性别与EHM风险无关。主要局限性在于这是一项存在一些记录缺陷的回顾性分析。可以得出结论，在此次疫情期间，品种是发生EHM的一个重要风险因素。
