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缺血性中风超急性处理的最新进展

An update on hyper-acute management of ischaemic stroke.

作者信息

Bhalla Ajay, Patel Mehool, Birns Jonathan

机构信息

St Thomas' Hospital, London, UK

University Hospital Lewisham, Lewisham, UK.

出版信息

Clin Med (Lond). 2021 May;21(3):215-221. doi: 10.7861/clinmed.2020-0998. Epub 2021 May 4.

DOI:10.7861/clinmed.2020-0998
PMID:33947658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8140712/
Abstract

This article aims to provide a comprehensive overview of key advances on various aspects of hyper-acute management of acute ischaemic stroke. These include neuroimaging, acute stroke unit care, management of blood pressure, reperfusion therapy including intravenous thrombolysis, mechanical thrombectomy and decompressive hemicraniectomy for malignant stroke syndrome. The challenge ahead is to ensure these evidence-based treatments are now being delivered and implemented to maximise the benefits across the population.

摘要

本文旨在全面概述急性缺血性脑卒中超急性期管理各方面的关键进展。这些进展包括神经影像学、急性卒中单元护理、血压管理、再灌注治疗,如静脉溶栓、机械取栓以及针对恶性卒中综合征的减压性颅骨切除术。未来面临的挑战是确保这些基于证据的治疗方法能够得到应用和实施,以使整个人群获得最大益处。

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本文引用的文献

1
Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.基于高级影像学指导的不明起病时间的卒中患者静脉内使用阿替普酶:个体化患者数据的系统评价和荟萃分析。
Lancet. 2020 Nov 14;396(10262):1574-1584. doi: 10.1016/S0140-6736(20)32163-2. Epub 2020 Nov 8.
2
Computed Tomography Perfusion After Thrombectomy: An Immediate Surrogate Marker of Outcome After Recanalization in Acute Stroke.急性卒中血管再通后 CT 灌注:即刻的转归替代标志物
Stroke. 2020 Jun;51(6):1736-1742. doi: 10.1161/STROKEAHA.120.029212. Epub 2020 May 14.
3
Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke.血管内血栓切除术联合或不联合静脉内阿替普酶治疗急性脑卒中。
N Engl J Med. 2020 May 21;382(21):1981-1993. doi: 10.1056/NEJMoa2001123. Epub 2020 May 6.
4
Organised inpatient (stroke unit) care for stroke: network meta-analysis.中风的有组织住院(中风单元)护理:网状Meta分析
Cochrane Database Syst Rev. 2020 Apr 23;4(4):CD000197. doi: 10.1002/14651858.CD000197.pub4.
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Management of acute ischemic stroke.急性缺血性脑卒中的管理。
BMJ. 2020 Feb 13;368:l6983. doi: 10.1136/bmj.l6983.
6
Review of Perfusion Imaging in Acute Ischemic Stroke: From Time to Tissue.急性缺血性卒中灌注成像综述:从时间到组织
Stroke. 2020 Mar;51(3):1017-1024. doi: 10.1161/STROKEAHA.119.028337. Epub 2020 Feb 3.
7
Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.急性缺血性脑卒中患者早期管理指南:2018 年急性缺血性脑卒中早期管理指南的更新:美国心脏协会/美国卒中协会发布的医疗保健专业人员指南。
Stroke. 2019 Dec;50(12):e344-e418. doi: 10.1161/STR.0000000000000211. Epub 2019 Oct 30.
8
Evidence that Tenecteplase Is Noninferior to Alteplase for Acute Ischemic Stroke: Meta-Analysis of 5 Randomized Trials.替奈普酶与阿替普酶治疗急性缺血性脑卒中非劣效性的证据:5 项随机试验的荟萃分析。
Stroke. 2019 Aug;50(8):2156-2162. doi: 10.1161/STROKEAHA.119.025080. Epub 2019 Jul 18.
9
Maximising access to thrombectomy services for stroke in England: A modelling study.英格兰卒中血栓切除术服务可及性最大化:一项模型研究。
Eur Stroke J. 2019 Mar;4(1):39-49. doi: 10.1177/2396987318785421. Epub 2018 Jul 19.
10
Extending thrombolysis to 4·5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data.将溶栓时间延长至 4.5-9 小时并用灌注成像进行唤醒性卒中治疗:一项个体患者数据的系统评价和荟萃分析。
Lancet. 2019 Jul 13;394(10193):139-147. doi: 10.1016/S0140-6736(19)31053-0. Epub 2019 May 22.