Arp L H, Leyh R D, Griffith R W
Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames 50011.
Am J Vet Res. 1988 May;49(5):693-6.
Adherence to turkey tracheal mucosa and agglutination of guinea pig erythrocytes were determined for 20 strains of Bordetella avium. Ten type-I strains, 7 type-II strains, 2 transposon-induced mutants, and 1 revertant were evaluated. All type-I strains adhered readily to tracheal mucosa and agglutinated erythrocytes, whereas no type-II strains adhered to trachea or caused hemagglutination (HA). Two mutants selected for loss of HA activity were less adherent to tracheal mucosa, compared with the parent strain. Reversion of one mutant to HA-positive status was accompanied by reconstitution of much of its adherence capacity. Results of this study provide preliminary evidence that tracheal adherence and HA of B avium are closely related.
对20株鸟博德特氏菌测定了其对火鸡气管黏膜的黏附情况以及对豚鼠红细胞的凝集情况。评估了10株I型菌株、7株II型菌株、2株转座子诱导突变体和1株回复突变体。所有I型菌株都能很容易地黏附于气管黏膜并凝集红细胞，而没有II型菌株能黏附于气管或引起血凝（HA）。与亲本菌株相比，选择的2株丧失HA活性的突变体对气管黏膜的黏附性较低。其中一个突变体回复到HA阳性状态伴随着其大部分黏附能力的恢复。本研究结果提供了初步证据，表明鸟博德特氏菌的气管黏附与HA密切相关。
