Shokrpoor Sara, Pedram Mirsepehr, Torjani Niyousha, Khoshvaghti Reza
Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Department of Radiology and Surgery, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Vet Res Forum. 2021 Winter;12(1):129-131. doi: 10.30466/vrf.2020.119465.2824. Epub 2021 Mar 15.
Myxoma is a benign mesenchymal tumor of skin and soft connective tissues considered to be of fibroblastic origin. A female bearded dragon () with a raised mass on the left side of the body was referred to the Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran. The mass had become evident and grew more extensive within the previous 11-month period. The dragon was anesthetized with 5.00% isoflurane, and the mass was removed surgically. Tissue samples of the mass were fixed in 10.00% neutral buffered formalin, sectioned and stained with Hematoxylin and Eosin (H&E), Alcian blue (pH: 2.50), and periodic acid Schiff (PAS) staining techniques. The patient was administered meloxicam, lincomycin, and marbofloxacin. Histopathologically, the capsulated mass was composed of myxoid structure. Stellate-to-reticular cells distributed in a mucinous stroma containing few tiny blood vessels were seen. Myxoid cells displayed a PAS-positive cytoplasm. The myxomatous matrix was alcianophilic at the pH of 2.50. To our knowledge, this is the first report of surgery, treatment, and histopathological study of myxoma in a bearded dragon (). The sutures were also removed 12 days after the operation. No new growth of the mass was observed three months following the surgical procedures.
黏液瘤是一种起源于成纤维细胞的皮肤和软组织良性间充质肿瘤。一只身体左侧有肿块隆起的雌性鬃狮蜥被转诊至伊朗德黑兰的德黑兰大学兽医学院。该肿块在之前11个月内变得明显且范围扩大。用5.00%异氟醚对蜥蜴进行麻醉，然后手术切除肿块。将肿块的组织样本固定在10.00%中性缓冲福尔马林中，切片并用苏木精和伊红（H&E）、阿尔辛蓝（pH：2.50）和过碘酸希夫（PAS）染色技术染色。给患者使用了美洛昔康、林可霉素和马波沙星。组织病理学上，有包膜的肿块由黏液样结构组成。可见星状至网状细胞分布于含有少量微小血管的黏液基质中。黏液样细胞显示PAS阳性细胞质。黏液瘤基质在pH 2.50时呈阿尔辛蓝嗜染性。据我们所知，这是关于鬃狮蜥黏液瘤手术、治疗和组织病理学研究的首例报告。术后12天也拆除了缝线。手术后三个月未观察到肿块有新的生长。
