Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.
Infect Control Hosp Epidemiol. 2022 Aug;43(8):1067-1069. doi: 10.1017/ice.2021.151. Epub 2021 May 7.
Previously reported associations between hospital-level antibiotic use and hospital-onset infection (HO-CDI) were reexamined using 2012-2018 data from a new cohort of US acute-care hospitals. This analysis revealed significant positive associations between total, third-generation, and fourth-generation cephalosporin, fluoroquinolone, carbapenem, and piperacillin-tazobactam use and HO-CDI rates, confirming previous findings.
先前报道的医院层面抗生素使用与医院获得性感染（HO-CDI）之间的关联，使用来自美国新的急性护理医院队列的 2012-2018 年数据进行了重新检查。该分析显示总剂量、第三代和第四代头孢菌素、氟喹诺酮类药物、碳青霉烯类药物和哌拉西林-他唑巴坦使用与 HO-CDI 发生率之间存在显著正相关，证实了先前的发现。
