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吸入式麻醉剂、臭氧损耗和温室效应:环境缓解工作的基础知识和现状。

Inhalational anaesthetics, ozone depletion, and greenhouse warming: the basics and status of our efforts in environmental mitigation.

机构信息

Department of Cardiothoracic Anaesthesia, Critical Care and ECMO.

Department of Anaesthesia, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester.

出版信息

Curr Opin Anaesthesiol. 2021 Aug 1;34(4):415-420. doi: 10.1097/ACO.0000000000001009.

Abstract

PURPOSE OF REVIEW

Following their use for medicinal purposes, volatile inhalational anaesthetic agents are expelled into the atmosphere where they contribute to anthropogenic climate change. We describe recent evidence examining the benefits and harms associated with their use.

RECENT FINDINGS

The environmental harms associated with desflurane and nitrous oxide likely outweigh any purported clinical benefits. Life cycle analyses are beginning to address the many gaps in our understanding, and informing choices made on all aspects of anaesthetic care. There is, however, an urgent need to move beyond the debate about anaesthetic technique A vs. B and focus also on areas such as sustainable procurement, waste management, pharmacological stewardship and joined-up solutions.

SUMMARY

There is now compelling evidence that anaesthetists, departments and hospitals should avoid desflurane completely, and limit nitrous oxide use to settings where there is no viable alternative, as their environmental harms outweigh any perceived clinical benefit. Life cycle analyses seem supportive of total intravenous and/or regional anaesthesia. There are many other areas where choices can be made by individual anaesthetists that contribute towards reducing the environmental burden of healthcare, such as prioritising the reduction of inappropriate resource use and over-treatment. However, this all requires joined up solutions where all parts of an organisation engage.

摘要

目的综述

挥发性吸入麻醉剂在被用于医疗目的后会被排放到大气中,从而导致人为气候变化。我们描述了最近的证据,这些证据检查了与它们的使用相关的益处和危害。

最近的发现

与地氟烷和氧化亚氮相关的环境危害可能超过任何据称的临床益处。生命周期分析开始解决我们理解中的许多空白,并为麻醉护理的各个方面的决策提供信息。然而,现在迫切需要超越关于麻醉技术 A 与 B 的争论,也关注可持续采购、废物管理、药理学管理以及联合解决方案等领域。

总结

现在有确凿的证据表明,麻醉师、部门和医院应完全避免使用地氟烷,并将氧化亚氮的使用限制在没有可行替代品的环境中,因为它们的环境危害超过了任何被认为的临床益处。生命周期分析似乎支持全静脉和/或区域麻醉。在减少医疗保健对环境的负担方面,还有许多其他领域可以由个别麻醉师做出选择,例如优先减少不当的资源使用和过度治疗。然而,这一切都需要组织各部分共同参与的联合解决方案。

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