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由复方新诺明和莫西沙星成功治疗的足菌肿。

Mycetoma due to Treated Successfully with Cotrimoxazole and Moxifloxacin.

作者信息

Bhandari Molisha, Kathuria Sushruta, Khunger Niti, Sharma Bhawna

机构信息

Department of Dermatology and STD, Safdarjung Hospital and Vardhaman Mahavir Medical College, Ansari Nagar, New Delhi, India.

Department of Microbiology, Safdarjung Hospital and Vardhaman Mahavir Medical College, Ansari Nagar, New Delhi, India.

出版信息

Indian Dermatol Online J. 2021 Feb 22;12(2):298-301. doi: 10.4103/idoj.IDOJ_533_20. eCollection 2021 Mar-Apr.

Abstract

is a recently identified organism and has rarely been reported to cause mycetoma. Here we report the case of a 40-year-old woman who presented with discharging sinuses and nodules for the past 7 years along with few discrete axillary lymph nodes. Cultures and Maldi-TOF MS (Matrix-assisted laser desorption/ionization-time of flight mass spectrometry) method identified the causative organism as The organism was acid-fast positive on modified Ziehl-Neelsen stain and Gram's stain revealed branched filamentous beaded gram-positive bacilli, while histopathology showed granulation tissue along with few ill-defined epithelioid cell granulomas, with giant cells. Based on the sensitivity report, the patient was started on tablet moxifloxacin and cotrimoxazole, and has shown considerable improvement at 2.5 months of follow-up.

摘要

是一种最近才被发现的生物体,很少有报道称其会引起足菌肿。在此,我们报告一例40岁女性病例,该患者在过去7年中出现了有分泌物的窦道和结节,同时伴有少数散在的腋窝淋巴结。通过培养和基质辅助激光解吸/电离飞行时间质谱(Maldi-TOF MS)方法确定病原体为 。该生物体在改良齐-尼氏染色上呈抗酸阳性,革兰氏染色显示为分支丝状念珠状革兰氏阳性杆菌,而组织病理学显示有肉芽组织以及少数界限不清的上皮样细胞肉芽肿,并伴有巨细胞。根据药敏报告,患者开始服用莫西沙星片和复方新诺明,在随访2.5个月时已显示出显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1fd/8088171/d343a967b770/IDOJ-12-298-g001.jpg

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