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病例报告:在一名34个月大的脑炎患儿脑脊液中检测到严重急性呼吸综合征冠状病毒2型

Case Report: Detection of SARS-CoV-2 From Cerebrospinal Fluid in a 34-Month-Old Child With Encephalitis.

作者信息

Cheraghali Fatemeh, Tahamtan Alireza, Hosseini Seyed Ahmad, Gharib Mohammad Hadi, Moradi Abdolvahab, Razavi Nikoo Hadi, Tabarraei Alijan

机构信息

Department of Pediatrics, School of Medicine, Taleghani Children's Hospital, Golestan University of Medical Sciences, Gorgan, Iran.

Infectious Diseases Research Centre, Golestan University of Medical Sciences, Gorgan, Iran.

出版信息

Front Pediatr. 2021 Apr 20;9:565778. doi: 10.3389/fped.2021.565778. eCollection 2021.

Abstract

Novel coronavirus (severe acute respiratory syndrome-coronavirus-2: SARS-CoV-2), which arose from Wuhan, China, has rapidly spread to other countries and developed into a pandemic. Although the respiratory manifestations of SARS-CoV-2 are well-documented, there is a considerable challenge regarding the direct and/or indirect infection in other organs. Several preliminary reports confirmed neurological manifestations in the SARS-CoV-2-infected patients. Here, we report the detection of SARS-CoV-2 from the nasopharyngeal swab and cerebrospinal fluid (CSF) in a 34-month-old child with encephalitis. This finding expands the spectrum of the neurological manifestations associated with SARS-CoV-2 infection.

摘要

新型冠状病毒(严重急性呼吸综合征冠状病毒2:SARS-CoV-2)起源于中国武汉,已迅速传播到其他国家并发展成为全球大流行。尽管SARS-CoV-2的呼吸道表现已有充分记录,但在其他器官的直接和/或间接感染方面仍存在相当大的挑战。几份初步报告证实了SARS-CoV-2感染患者存在神经学表现。在此,我们报告了一名34个月大患脑炎儿童的鼻咽拭子和脑脊液(CSF)中检测到SARS-CoV-2。这一发现扩展了与SARS-CoV-2感染相关的神经学表现谱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07db/8093448/3cbcd361c913/fped-09-565778-g0001.jpg

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