Businco L, Cantani A, Farinella F, Businco E
Department of Paediatrics, University of Rome La Sapienza, Italy.
Clin Allergy. 1988 May;18(3):269-74. doi: 10.1111/j.1365-2222.1988.tb02869.x.
This report describes a retrospective analysis of the month of birth distribution of 2124 children with respiratory allergy in the Rome district between 1964 and 1985, in comparison with the total live births in the same district over the same period. Of the 2124 children, 1685 had positive skin tests and/or RAST only to mites, and 439 only to grass pollen (P much less than 0.001). A significant relationship was found between grass or mite sensitization and the month of birth. A high proportion of children born in June-September had mite allergy (P less than 0.005), and even higher was that of those born in March-May with grass sensitivity (P much less than 0.005), compared with the total live birth distribution in the Rome district in the same years as the children examined. These results are consistent with the idea that allergy may be associated with a period of susceptibility to sensitization in early infancy.
本报告描述了对1964年至1985年罗马地区2124例患有呼吸道过敏儿童的出生月份分布进行的回顾性分析，并与同期该地区的总活产数进行了比较。在这2124名儿童中，1685名仅对螨虫的皮肤试验和/或放射性变应原吸附试验呈阳性，439名仅对草花粉呈阳性（P远小于0.001）。发现草或螨虫致敏与出生月份之间存在显著关系。与所检查儿童同年的罗马地区总活产分布相比，6月至9月出生的儿童中对螨虫过敏的比例较高（P小于0.005），3月至5月出生的儿童对草敏感的比例甚至更高（P远小于0.005）。这些结果与过敏可能与婴儿早期易致敏期有关的观点一致。
