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一例支气管内放线菌病作为肺不张的一个具有挑战性的病因。

A case of endobronchial actinomycosis as a challenging cause of lung atelectasis.

作者信息

Golfi Nicoletta, Mastriforti Roberta, Guidelli Luca, Scala Raffaele

机构信息

Pulmonology and RICU, S Donato Hospital, Arezzo, Italy.

Internal Medicine, S Sepolcro Hospital, Arezzo, Italy.

出版信息

BMC Infect Dis. 2021 May 8;21(1):433. doi: 10.1186/s12879-021-06126-3.

DOI:10.1186/s12879-021-06126-3
PMID:33964874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8105992/
Abstract

BACKGROUND

Primary endobronchial actinomycosis is exceptionally uncommon and can be misdiagnosed as unresolving pneumonia, endobronchial lipoma, bronchogenic carcinoma or foreign body. Predisposing factors are immunosuppressive conditions, chronic lung diseases, poor oral hygiene or foreign body aspiration.

CASE PRESENTATION

We reported a case of 88-year old woman with a 4 days history of mild exertional dyspnea, productive cough with purulent sputum and fever up to 37.8 °C, who developed left sided endobronchial actinomycosis in absence of any pre-existent risk conditions; endobronchial de-obstruction and specific antibiotic treatment were performed with success, achieving a full resolution of the disease, with bronchoscopy playing a key role in the diagnosticand therapeutic pathways.

CONCLUSIONS

This case raises the necessity for increased awareness in the management of endobronchial lesions and in cases of suspected endobronchial actinomycosis; bronchoscopy plays a key role in the diagnostic and therapeutic process; prompt recognition of this entity can expedite proper treatment and recovery.

摘要

背景

原发性支气管放线菌病极为罕见,可能被误诊为迁延不愈的肺炎、支气管内脂肪瘤、支气管癌或异物。诱发因素包括免疫抑制状态、慢性肺部疾病、口腔卫生差或异物吸入。

病例介绍

我们报告了一例88岁女性病例,患者有4天轻度劳力性呼吸困难、咳脓性痰的咳嗽及体温高达37.8°C发热的病史,在无任何既往风险因素的情况下发生了左侧支气管放线菌病;进行了支气管内解除梗阻及特异性抗生素治疗,成功治愈疾病,支气管镜检查在诊断和治疗过程中发挥了关键作用。

结论

该病例凸显了提高对支气管内病变及疑似支气管放线菌病病例管理认识的必要性;支气管镜检查在诊断和治疗过程中起关键作用;及时识别该疾病可加快恰当治疗及康复。

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Interstitial Lung Fibrosis Imaging Reporting and Data System: What Radiologist Wants to Know?间质性肺纤维化影像报告和数据系统:放射科医生想了解什么?
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A 35-year old woman with productive cough and breathlessness.一名35岁的女性,伴有咳痰和呼吸急促症状。
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Pulmonary actinomycosis with endobronchial involvement: a case report and literature review.累及支气管内的肺放线菌病:一例报告及文献复习
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Actinomycosis.放线菌病
BMJ. 2011 Oct 11;343:d6099. doi: 10.1136/bmj.d6099.
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Bronchopulmonary actinomycosis associated with hiatal hernia.与食管裂孔疝相关的支气管肺放线菌病。
Mayo Clin Proc. 2009 Feb;84(2):123-8. doi: 10.4065/84.2.123.
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Thoracic actinomycosis: CT features with histopathologic correlation.胸段放线菌病:CT特征与组织病理学对照
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Short-term treatment of actinomycosis: two cases and a review.放线菌病的短期治疗:两例病例及文献综述
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