大麻二酚在神经紊乱中的作用。
The Role of Cannabidiol in Neurological Disorders.
机构信息
Department of Neurology, Kaiser Permanente Medical Center, Orange County, CA.
出版信息
Perm J. 2021 May;25. doi: 10.7812/TPP/20.156.
Abstract
Cannabis has been used for both recreational and medicinal purposes for more than 4 millennia. Cannabis has been studied in various medical disorders including neurological disorders. There are well-known risks of long-term use of cannabis, including low motivation, lowered cognitive capabilities, and diminished IQ and brain mass. Cannabinoids are compounds in cannabis that are known to have therapeutic potential. The most abundant chemicals in cannabinoids are delta-9-tetrahydrocannabinol and cannabidiol. Delta-9-tetrahydrocannabinol has psychotropic effects that limits its use as a pharmacotherapeutic agent. Cannabidiol is a nonpsychotropic chemical and therefore has become a compound of interest for clinical researchers to study its therapeutic potential. This article reviews the efficacy and safety of cannabidiol in various neurological disorders in humans.
摘要
大麻已经被用于娱乐和医疗目的超过 4000 年。大麻已经在各种医学疾病中进行了研究，包括神经疾病。长期使用大麻有众所周知的风险，包括低动力、认知能力下降以及智商和大脑质量下降。大麻素是大麻中的化合物，已知具有治疗潜力。大麻素中最丰富的化学物质是 delta-9-四氢大麻酚和大麻二酚。Delta-9-四氢大麻酚具有致幻作用，限制了它作为药物治疗剂的使用。大麻二酚是一种非致幻化学物质，因此已成为临床研究人员研究其治疗潜力的化合物。本文综述了大麻二酚在人类各种神经疾病中的疗效和安全性。
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