Robinet-Lévy M, Yuasa I, Umetsu K, Ikebuchi J
Institut d'Hématologie, Centre de Transfusion Sanguine, Montpellier, France.
Hum Hered. 1988;38(3):174-7. doi: 10.1159/000153780.
A French population was investigated for genetic polymorphism of alpha 2HS-glycoprotein (A2HS; nomenclature according to Human Gene Mapping 7, Los Angeles, 1983) using isoelectric focusing and immunoblotting. Three variants were observed together with two common alleles A2HS 1 and A2HS 2, whose frequencies were significantly different from the data in Canadians and Egyptians. An anodal variant to A2HS 1 was identical to a variant with two different nomenclatures reported by three different groups, indicating that there is a confusion in the A2HS nomenclature. The others were new variants with cathodal isoelectric points to A2HS 2 in the native state.
利用等电聚焦和免疫印迹法对一组法国人群的α2HS-糖蛋白（A2HS；根据1983年洛杉矶人类基因图谱7的命名法）进行了遗传多态性研究。观察到三个变体以及两个常见等位基因A2HS 1和A2HS 2，它们的频率与加拿大人和埃及人的数据有显著差异。A2HS 1的一个阳极变体与三个不同研究小组报道的具有两种不同命名法的变体相同，这表明A2HS的命名存在混淆。其他变体是天然状态下相对于A2HS 2具有阴极等电点的新变体。
