Umetsu K, Kashimura S, Ikeda N, Suzuki T
Hum Genet. 1984;67(1):70-1. doi: 10.1007/BF00270561.
Isoelectric focusing (pH 4.0-5.0) of serum alpha 2HS-glycoprotein on polyacrylamide gels has been found to be a useful tool in population genetics and forensic science. Using this method, we isolated three common types, alpha 2HS 1-1, alpha 2HS 2-1 and alpha 2HS 2-2, and showed that alpha 2HS types are determined by two autosomal codominant alleles, alpha 2HS1 and alpha 2HS2. The method is simple, fast and easy to perform. Results of typing for the two alleles, alpha 2HS1 and alpha 2HS2, are described for a Japanese population sample (n = 1003).
在聚丙烯酰胺凝胶上对血清α2HS-糖蛋白进行等电聚焦（pH 4.0 - 5.0）已被证明是群体遗传学和法医学中的一种有用工具。使用这种方法，我们分离出了三种常见类型，即α2HS 1-1、α2HS 2-1和α2HS 2-2，并表明α2HS类型由两个常染色体共显性等位基因α2HS1和α2HS2决定。该方法简单、快速且易于操作。描述了对日本人群样本（n = 1003）中α2HS1和α2HS2这两个等位基因的分型结果。
