Department of Urology and Kidney Transplantation, Aix-Marseille University, APHM, Conception University Hospital, Marseilles, France.
Department of Otorhinolaryngology- Head & Neck Surgery, APHM, Aix-Marseille University, Conception University Hospital, Marseilles, France.
PLoS One. 2021 May 11;16(5):e0251122. doi: 10.1371/journal.pone.0251122. eCollection 2021.
To assess the risk of postoperative SARS-CoV-2 infection during the COVID-19 pandemic.
The CONCEPTION study was a cohort, multidisciplinary study conducted at Conception University Hospital, in France, from March 17th to May 11th, 2020. Our study included all adult patients who underwent minor surgery in one of the seven surgical departments of our hospital: urology, digestive, plastic, gynecological, otolaryngology, gynecology or maxillofacial surgery. Preoperative self-isolation, clinical assessment using a standardized questionnaire, physical examination, nasopharyngeal RT-PCR and chest CT scan performed the day before surgery were part of our active prevention strategy. The main outcome was the occurrence of a SARS-CoV-2 infection within 21 days following surgery. The COVID-19 status of patients after discharge was updated during the postoperative consultation and to ensure the accuracy of data, all patients were contacted again by telephone.
A total of 551 patients from six different specialized surgical Departments in our tertiary care center were enrolled in our study. More than 99% (546/551) of included patients underwent a complete preoperative Covid-19 screening including RT-PCR testing and chest CT scan upon admission to the Hospital. All RT-PCR tests were negative and in 12 cases (2.2%), preoperative chest CT scans detected pulmonary lesions consistent with the diagnosis criteria for COVID-19. No scheduled surgery was postponed. One patient (0.2%) developed a SARS-CoV-2 infection 20 days after a renal transplantation. No readmission or COVID-19 -related death within 30 days from surgery was recorded.
Minor surgery remained safe in the COVID-19 Era, as long as all appropriate protective measures were implemented. These data could be useful to public Health Authorities in order to improve surgical patient flow during a pandemic.
评估 COVID-19 大流行期间术后 SARS-CoV-2 感染的风险。
CONCEPTION 研究是一项队列、多学科研究,于 2020 年 3 月 17 日至 5 月 11 日在法国的 Conception 大学医院进行。我们的研究包括在我院七个外科部门之一接受小手术的所有成年患者:泌尿科、消化科、整形外科、妇科、耳鼻喉科、妇科或颌面外科。术前自我隔离、使用标准化问卷进行临床评估、体检、手术前一天进行鼻咽 RT-PCR 和胸部 CT 扫描是我们主动预防策略的一部分。主要结局是手术后 21 天内发生 SARS-CoV-2 感染。在术后咨询期间更新患者出院后的 COVID-19 状态,并通过电话再次联系所有患者以确保数据的准确性。
我们的三级保健中心的六个不同专业外科部门共纳入了 551 名患者。超过 99%(546/551)的纳入患者接受了完整的术前 COVID-19 筛查,包括入院时的 RT-PCR 检测和胸部 CT 扫描。所有 RT-PCR 检测均为阴性,12 例(2.2%)术前胸部 CT 扫描显示与 COVID-19 诊断标准一致的肺部病变。没有推迟任何择期手术。1 例(0.2%)肾移植后 20 天发生 SARS-CoV-2 感染。术后 30 天内无再入院或 COVID-19 相关死亡记录。
只要采取所有适当的保护措施,COVID-19 时代的小手术仍然是安全的。这些数据可能对公共卫生当局有用,以便在大流行期间改善外科患者流程。