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巨大的颈侧肿块:异位甲状腺恶性肿瘤。

Massive lateral neck mass: aberrant ectopic thyroid malignancy.

机构信息

Department of Pathology, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.

Department of Pathology, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India

出版信息

BMJ Case Rep. 2021 May 11;14(5):e241451. doi: 10.1136/bcr-2020-241451.

DOI:10.1136/bcr-2020-241451
PMID:33975840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8118039/
Abstract

Lateral aberrant ectopic thyroid is very rare, comprising only 1%-3% of all the ectopic thyroid tissue. Clinically, these lesions are mistaken for lymph node swelling or metastatic tumour. Primary carcinoma in lateral aberrant ectopic thyroid with normal active native thyroid is very uncommon. We report a case of papillary carcinoma in lateral aberrant ectopic thyroid tissue, with a completely normal native thyroid gland in a 53-year-old man, who presented with a massive swelling in the lateral aspect of the neck clinically and radiologically diagnosed as a malignant soft tissue tumour with differential diagnosis of malignant lymphoma. Fine needle aspiration cytology revealed metastatic papillary carcinoma. In toto excision of the soft tissue mass along with subtotal thyroidectomy was performed. Histology of the mass revealed papillary carcinoma of lateral aberrant ectopic thyroid, while the thyroid gland did not show evidence of malignancy. The postsurgical period was uneventful, and the patient underwent radioiodine ablation.

摘要

侧方异位甲状腺非常罕见,仅占所有异位甲状腺组织的 1%-3%。临床上,这些病变被误诊为淋巴结肿大或转移性肿瘤。在正常活动的固有甲状腺正常的侧方异位甲状腺中,原发性癌非常罕见。我们报告了一例 53 岁男性患者的侧方异位甲状腺组织中的乳头状癌,该患者的固有甲状腺完全正常,临床上表现为颈部侧方巨大肿胀,放射学诊断为恶性软组织肿瘤,鉴别诊断为恶性淋巴瘤。细针穿刺细胞学显示转移性乳头状癌。我们对软组织肿块进行了整块切除,并进行了甲状腺次全切除术。肿块的组织学显示侧方异位甲状腺的乳头状癌,而甲状腺没有恶性的证据。术后情况良好,患者接受了放射性碘消融治疗。

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Comparative Analysis of Metastatic Thyroid Carcinoma versus Ectopic Thyroid Carcinoma in Lateral Neck Masses without Identifiable Primary Thyroid Carcinoma.无明确原发性甲状腺癌的侧颈部肿块中转移性甲状腺癌与异位甲状腺癌的对比分析
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本文引用的文献

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Ectopic Papillary Carcinoma in the Midline Neck Accompanied by a Benign Thyroid Gland.中线颈部异位乳头状癌伴良性甲状腺
Case Rep Otolaryngol. 2019 Jan 10;2019:9172942. doi: 10.1155/2019/9172942. eCollection 2019.
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Papillary Thyroid Carcinoma: Ectopic Malignancy versus Metastatic Disease.甲状腺乳头状癌:异位恶性肿瘤与转移性疾病
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BMJ Case Rep. 2012 Jul 9;2012:bcr0220125783. doi: 10.1136/bcr.02.2012.5783.
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Cervical lymphadenopathy: metastasis of papillary carcinoma or ectopic thyroid tissue?颈部淋巴结病:乳头状癌转移还是异位甲状腺组织?
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Ectopic thyroid tissue: anatomical, clinical, and surgical implications of a rare entity.异位甲状腺组织:一种罕见实体的解剖、临床和外科意义。
Eur J Endocrinol. 2011 Sep;165(3):375-82. doi: 10.1530/EJE-11-0461. Epub 2011 Jun 29.
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A case of an ectopic thyroid gland at the lateral neck masquerading as a metastatic papillary thyroid carcinoma.一例位于侧颈部的异位甲状腺,伪装成转移性甲状腺乳头状癌。
J Korean Med Sci. 2008 Jun;23(3):548-50. doi: 10.3346/jkms.2008.23.3.548.
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A case of branchial cyst with an ectopic thyroid papillary carcinoma.1例伴有异位甲状腺乳头状癌的鳃裂囊肿。
Ann Ital Chir. 2004 May-Jun;75(3):349-51; discussion 352.
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Evolution and evaluation of lateral cystic neck masses containing thyroid tissue: "lateral aberrant thyroid" revisited.
Am J Otolaryngol. 1996 Jan-Feb;17(1):12-5. doi: 10.1016/s0196-0709(96)90036-8.