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加纳阿克拉科勒-布教学医院收治的新冠肺炎患者的临床特征。

Clinical characteristics of COVID-19 patients admitted at the Korle-Bu Teaching Hospital, Accra, Ghana.

作者信息

Adjei Patrick, Afriyie-Mensah Jane, Ganu Vincent J, Puplampu Peter, Opoku-Asare Bismark, Dzefi-Tettey Klenam, Amissah-Arthur Maame-Boatemaa, Tachi Kenneth, Boima Vincent, Dey Dzifa, Akamah Joseph, Akpalu Albert, Akpalu Josephine, Amoo Phillip, Otchi Elom, Marfoh Kissinger, Agyei-Nkansah Adwoa

机构信息

Department of Medicine and Therapeutics, University of Ghana Medical School, University of Ghana, Accra, Ghana.

Department of Medicine, Korle Bu Teaching Hospital, Accra, Ghana.

出版信息

Ghana Med J. 2020 Dec;54(4 Suppl):33-38. doi: 10.4314/gmj.v54i4s.6.

DOI:10.4314/gmj.v54i4s.6
PMID:33976439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8087357/
Abstract

UNLABELLED

The study examined the clinical characteristics and outcomes of 2019 novel coronavirus disease (COVID-19) infections among hospitalized patients.

DESIGN

Study design was a retrospective single-center review of hospital data.

SETTING

The study was conducted at the COVID-19 Treatment Center of the Department of Medicine and Therapeutics of the Korle-Bu Teaching hospital in Accra, Ghana.

PARTICIPANTS AND STUDY TOOLS

A total of fifty patients with laboratory (rRT-PCR) confirmed COVID-19 infection were involved in the study. A chart review of the medical records of the patients was conducted and the data obtained was documented using a data extraction form.

RESULTS

The median age was 53 years and most (36% (18/50)) of the patients were at least 60 years of age. Eighty percent (40/50) of the patients were symptomatic, with cough and difficulty in breathing being the commonest presenting symptoms. The mean duration of hospitalization was 12.3 ± 7.3 days. Hypertension and Diabetes Mellitus were the commonest co-morbidities occurring in 52% (26/50) and 42% (21/50) of patients respectively. Fifty percent of patients developed COVID-19 pneumonia as a complication. The mortality rate was 12% (6/50).

CONCLUSION

In this study, SARS-CoV2 infection affected older adults with hypertension and diabetes mellitus being the common comorbidities. Patients with these comorbid conditions should be counselled by their clinicians to strictly observe the COVID-19 prevention protocols to reduce their risk of acquiring the infection. There is a need to pay critical and prompt attention to the management of patients with COVID-19 pneumonia particularly among people with diabetes to improve outcomes.

FUNDING

None declared.

摘要

未标注

该研究调查了住院患者中2019新型冠状病毒病(COVID-19)感染的临床特征和结局。

设计

研究设计为对医院数据的回顾性单中心分析。

背景

该研究在加纳阿克拉科尔勒-布教学医院医学与治疗学部的COVID-19治疗中心进行。

参与者和研究工具

共有50例经实验室(逆转录-聚合酶链反应[rRT-PCR])确诊的COVID-19感染患者参与了该研究。对患者的病历进行了图表回顾,并使用数据提取表记录所获得的数据。

结果

中位年龄为53岁,大多数患者(36%[18/50])至少60岁。80%(40/50)的患者有症状,咳嗽和呼吸困难是最常见的首发症状。平均住院时间为12.3±7.3天。高血压和糖尿病是最常见的合并症,分别发生在52%(26/50)和42%(21/50)的患者中。50%的患者发生COVID-19肺炎作为并发症。死亡率为12%(6/50)。

结论

在本研究中,严重急性呼吸综合征冠状病毒2(SARS-CoV2)感染影响老年人,高血压和糖尿病是常见的合并症。临床医生应建议患有这些合并症的患者严格遵守COVID-19预防方案,以降低感染风险。有必要对COVID-19肺炎患者,尤其是糖尿病患者的管理给予高度和及时的关注,以改善结局。

资金

未声明。