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加纳阿克拉两个国家治疗中心首批新冠康复者的社会人口学和临床特征

Sociodemographic and clinical characteristics of the first cohort of COVID-19 recoveries at two national treatment centres in Accra, Ghana.

作者信息

Owoo Christian, Oliver-Commey Joseph A, Calys-Tagoe Benedict N L, Oduro-Mensah Ebenezer, Ofori-Boadu Lawrence, Adjei-Mensah Evelyn, Kenu Ernest, Samba Ali, Yawson Alfred E, Lartey Margaret

机构信息

National COVID-19 Treatment Centre, University of Ghana Medical Centre (UGMC), Accra.

Department of Anaesthesia, University of Ghana Medical School, College of Health Sciences, University of Ghana, Accra.

出版信息

Ghana Med J. 2020 Dec;54(4 Suppl):16-22. doi: 10.4314/gmj.v54i4s.4.

Abstract

INTRODUCTION

COVID-19 is a new disease, knowledge on the mode of transmission and clinical features are still evolving, new tests are being developed with inherent challenges regarding interpretation of tests results. There is generally, a gap in knowledge on the virus globally as the pandemic evolves and in Ghana, there is dearth of information and documentation on the clinical characteristics of the virus. With these in mind, we set out to profile the initial cohort of COVID-19 patients who recovered in Ghana.

METHODS

We reviewed clinical records of all confirmed cases of COVID-19 who had recovered from the two main treatment centres in Accra, Ghana. Descriptive data analysis was employed and presented in simple and relational tables. Independent t-test and ANOVA were used to determine differences in the mean age of the sexes and the number of days taken for the first and second retesting to be done per selected patient characteristics.

RESULTS

Of the 146 records reviewed, 54% were male; mean age of patients was 41.9 ± 17.5 years, nearly half were asymptomatic, with 9% being severely ill. The commonest presenting symptoms were cough (22.6%), headache (13%) and sore throat (11%) while the commonest co-morbidities were hypertension (25.3%), diabetes mellitus (14%) and heart disease (3.4%).

CONCLUSION

COVID-19 affected more males than females; nearly half of those infected were asymptomatic. Cough, headache and sore throat were the commonest symptoms and mean duration from case confirmation to full recovery was 19 days. Further research is required as pandemic evolves.

FUNDING

None declared.

摘要

引言

新型冠状病毒肺炎(COVID-19)是一种新出现的疾病,关于其传播方式和临床特征的认识仍在不断发展,新的检测方法也在不断研发,但在检测结果的解读方面存在固有挑战。随着全球大流行的发展,人们对这种病毒的了解普遍存在差距,在加纳,关于该病毒临床特征的信息和文献也很匮乏。考虑到这些因素,我们着手对加纳康复的首批COVID-19患者进行分析。

方法

我们回顾了加纳阿克拉两个主要治疗中心所有确诊的COVID-19康复病例的临床记录。采用描述性数据分析,并以简单表格和关系表格呈现。使用独立样本t检验和方差分析来确定不同性别患者的平均年龄差异,以及根据所选患者特征进行首次和第二次重新检测所需天数的差异。

结果

在审查的146份记录中,54%为男性;患者的平均年龄为41.9±17.5岁,近一半患者无症状,9%为重症。最常见的症状是咳嗽(22.6%)、头痛(13%)和咽痛(11%),最常见的合并症是高血压(25.3%)、糖尿病(14%)和心脏病(3.4%)。

结论

COVID-19对男性的影响大于女性;近一半感染者无症状。咳嗽、头痛和咽痛是最常见的症状,从确诊到完全康复的平均持续时间为19天。随着大流行的发展,需要进一步研究。

资金来源

未声明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef13/8087372/7c9c1aadb0ac/GMJ5404s-0016Fig1.jpg

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