Abbas Manzar, Atiq Atia, Xing Ruirui, Yan Xuehai
Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.
Department of Physics, Division of Science and Technology, University of Education, Lahore, Pakistan.
J Mater Chem B. 2021 Jun 2;9(22):4444-4458. doi: 10.1039/d1tb00025j.
The natural biomolecules of peptides and proteins are able to form elegant metal incorporating supramolecular nanomaterials through multiple weak non-covalent interactions. The use of toxic chemical reagents to fabricate silver nanoparticles poses a danger to apply them in various biomedical applications. Peptide and protein biomolecules have the potential to overcome this barrier by the supramolecular chemistry approach. In this review, we focus on the self-assembly of peptides and proteins to synthesize silver incorporating supramolecular nanoarchitectures, which in turn enhance the biological properties of these silver nanomaterials being used in nanomedicine. This review aims to illustrate the recent developments in amphiphilic peptides, oligopeptides, collagen, bovine serum albumin (BSA), and human serum albumin (HSA) as capping, stabilizing, and reducing agents to form silver incorporating supramolecular nanostructures. Finally, we provide some biomedical applications of silver-incorporating supramolecular nanomaterials along with future perspectives.
肽和蛋白质等天然生物分子能够通过多种弱非共价相互作用形成优雅的含金属超分子纳米材料。使用有毒化学试剂制备银纳米颗粒对其在各种生物医学应用中的应用构成了危险。肽和蛋白质生物分子有潜力通过超分子化学方法克服这一障碍。在本综述中，我们重点关注肽和蛋白质的自组装以合成含银超分子纳米结构，这反过来又增强了这些用于纳米医学的银纳米材料的生物学特性。本综述旨在阐述两亲性肽、寡肽、胶原蛋白、牛血清白蛋白（BSA）和人血清白蛋白（HSA）作为封端、稳定和还原剂以形成含银超分子纳米结构的最新进展。最后，我们提供了含银超分子纳米材料的一些生物医学应用以及未来展望。
