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大流行的持久影响:以 1918 年阿根廷流感大流行为例。

Long-lasting effects of pandemics: The case of the 1918 influenza pandemic in Argentina.

机构信息

Instituto de Investigaciones Económicas y Sociales del Sur, Universidad Nacional del Sur/CONICET (IIESS, UNS-CONICET), San Andrés 800, Bahía Blanca-Buenos Aires.

Facultad de Ciencias Económicas, Universidad Nacional de Misiones, Ruta 12 Km 12.5, Posadas-Misiones.

出版信息

Spat Spatiotemporal Epidemiol. 2021 Jun;37:100409. doi: 10.1016/j.sste.2021.100409. Epub 2021 Jan 28.

DOI:10.1016/j.sste.2021.100409
PMID:33980404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9760832/
Abstract

The 2019 novel coronavirus disease pandemic poses a serious threat. While its short-term effects are evident, its long-term consequences are a matter of analysis. In this work, the existence of long-lasting negative effects derived from exposure in utero to a great pandemic -1918 influenza pandemic- is analysed for the Argentine case. Outcomes of interest include educational achievement and unemployment status in adulthood -50 years after the pandemic. Based on a regression analysis, temporal differences in the spread of the pandemic and between close birth cohorts are exploited. The results indicate a significant reduction in educational achievement for people exposed in utero to the pandemic. In the region with the highest incidence of cases (Noroeste), this reduction is 0.5 years of education. There are no significant changes in the chances of being unemployed. In the context of climate change, these results constitute a call of attention for the implementation of child protection policies from gestation.

摘要

2019 年新型冠状病毒病大流行构成了严重威胁。虽然其短期影响显而易见,但长期后果仍有待分析。在这项工作中,分析了在子宫内暴露于大流行(1918 年流感大流行)的情况下,阿根廷会出现长期负面后果的情况。感兴趣的结果包括 50 年后的成年时期的教育成就和失业状况。基于回归分析,利用了大流行传播和同期出生队列之间的时间差异。结果表明,对于在子宫内暴露于大流行的人来说,教育成就明显下降。在病例发生率最高的地区(西北部),这一降幅为 0.5 年的教育。失业的几率没有明显变化。在气候变化的背景下,这些结果呼吁从妊娠开始实施儿童保护政策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6225/9760832/7aab2789996d/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6225/9760832/ba08067252e6/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6225/9760832/7aab2789996d/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6225/9760832/ba08067252e6/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6225/9760832/7aab2789996d/gr2_lrg.jpg

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本文引用的文献

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The short-term economic consequences of COVID-19: Exposure to disease, remote work and government response.COVID-19 对短期经济的影响:疾病暴露、远程办公和政府应对。
PLoS One. 2023 Mar 15;18(3):e0270341. doi: 10.1371/journal.pone.0270341. eCollection 2023.
2
The Long-Lasting Influenza: The Impact of Fetal Stress During the 1918 Influenza Pandemic on Socioeconomic Attainment and Health in Sweden, 1968-2012.漫长的流感:1918 年流感大流行期间胎儿应激对瑞典 1968-2012 年社会经济成就和健康的影响。
Demography. 2019 Aug;56(4):1389-1425. doi: 10.1007/s13524-019-00799-x.
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大流行性流感对精英家庭背景儿童成长的长期影响:来自工业化进程中日本的证据。
Econ Hum Biol. 2018 Sep;31:125-137. doi: 10.1016/j.ehb.2018.08.012. Epub 2018 Sep 1.
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Does in utero exposure to Illness matter? The 1918 influenza epidemic in Taiwan as a natural experiment.子宫内暴露于疾病是否重要?以台湾1918年流感大流行作为一项自然实验。
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No consistent effects of prenatal or neonatal exposure to Spanish flu on late-life mortality in 24 developed countries.在24个发达国家,产前或新生儿期接触西班牙流感对晚年死亡率没有持续影响。
Demogr Res. 2010 Apr 13;22(20):579-634. doi: 10.4054/DemRes.2010.22.20.
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Long-lasting effects of undernutrition.营养不良的长期影响。
Int J Environ Res Public Health. 2011 Jun;8(6):1817-46. doi: 10.3390/ijerph8061817. Epub 2011 May 26.
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