Barbara J. Jester is a Battelle contractor working for the Influenza Division at Centers for Disease Control and Prevention (CDC), Atlanta, GA. Timothy M. Uyeki is chief medical officer for the Influenza Division at CDC. Anita Patel is the medical care and countermeasures team lead for the Influenza Coordination Unit at CDC. Lisa Koonin is deputy director of the Influenza Coordination Unit at CDC. Daniel B. Jernigan is director of the Influenza Division at CDC.
Am J Public Health. 2018 Nov;108(11):1469-1472. doi: 10.2105/AJPH.2018.304586. Epub 2018 Sep 25.
The 1918 influenza pandemic spread rapidly around the globe, leading to high mortality and social disruption. The countermeasures available to mitigate the pandemic were limited and relied on nonpharmaceutical interventions. Over the past 100 years, improvements in medical care, influenza vaccines, antiviral medications, community mitigation efforts, diagnosis, and communications have improved pandemic response. A number of gaps remain, including vaccines that are more rapidly manufactured, antiviral drugs that are more effective and available, and better respiratory protective devices.
1918 年流感大流行在全球迅速蔓延，导致高死亡率和社会混乱。可用于减轻大流行的对策有限，依赖于非药物干预措施。在过去的 100 年中，医疗保健、流感疫苗、抗病毒药物、社区缓解措施、诊断和通信方面的改进提高了大流行应对能力。仍存在一些差距，包括制造速度更快的疫苗、更有效和更可用的抗病毒药物以及更好的呼吸保护装置。
