Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca (CAUSA), Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (CIETUS), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, España.
Medicina Interna, Unidade Local de Saude de Guarda, Guarda, Portugal.
Epidemiol Infect. 2021 May 14;149:e149. doi: 10.1017/S0950268821001151.
Brucellosis remains one of the main zoonoses worldwide. Epidemiological data on human brucellosis in Spain are scarce. The objective of this study was to assess the epidemiological characteristics of inpatient brucellosis in Spain between 1997 and 2015. A retrospective longitudinal descriptive study was performed. Data were requested from the Health Information Institute of the Ministry of Health and Equality, which provided us with the Minimum Basic Data Set of patients admitted to the National Health System. We also obtained data published in the System of Obligatory Notifiable Diseases. A total of 5598 cases were registered. The period incidence rate was 0.67 (95% CI 0.65-0.68) cases per 100 000 person-years. We observed a progressive decrease in the number of cases and annual incidence rates. A total of 3187 cases (56.9%) came from urban areas. The group most at risk comprised men around the fifth decade of life. The average (±s.d.) hospital stay was 12.6 days (±13.1). The overall lethality rate of the cohort was 1.5%. The number of inpatients diagnosed with brucellosis decreased exponentially. The group of patients with the highest risk of brucellosis in our study was males under 45 years of age and of urban origin. The lethality rate has reduced to minimum values. It is probable that hospital discharge records could be a good database for the epidemiological analysis of the hospital management of brucellosis and offer a better information collection system than the notifiable diseases system (EDO in Spanish).
布鲁氏菌病仍然是全球主要的动物源性传染病之一。西班牙人类布鲁氏菌病的流行病学数据较为缺乏。本研究旨在评估 1997 年至 2015 年期间西班牙住院布鲁氏菌病的流行病学特征。采用回顾性纵向描述性研究方法。我们向卫生部和平等事务部的卫生信息研究所请求数据，该研究所为我们提供了国家卫生系统住院患者的最低基本数据集。我们还获取了在强制性法定传染病报告系统中公布的数据。共登记了 5598 例病例。期间发病率为 0.67（95%CI 0.65-0.68）/100000 人年。我们观察到病例数和年发病率呈逐渐下降趋势。3187 例（56.9%）来自城市地区。风险最高的人群是 50 岁左右的男性。平均（±s.d.）住院时间为 12.6 天（±13.1）。该队列的总病死率为 1.5%。诊断为布鲁氏菌病的住院患者人数呈指数下降。我们研究中布鲁氏菌病风险最高的患者群体为 45 岁以下的男性和城市居民。病死率已降至最低。医院出院记录可能是对布鲁氏菌病的医院管理进行流行病学分析的良好数据库，并提供了比法定传染病报告系统（西班牙文缩写为 EDO）更好的信息收集系统。
