Department of Oral Medicine and Radiology, Faculty of Dentistry, Sebha University, Sebha, Libya.
Faculty of Odontology, Malmö University, Malmö, Sweden.
Br J Radiol. 2021 Jul 1;94(1123):20210042. doi: 10.1259/bjr.20210042. Epub 2021 May 27.
To apply the ROBIS tool for assessment of risk of bias (RoB) in systematic reviews (SRs) in a meta-review on effective doses (EDs) in dental and maxillofacial cone beam CT.
Three electronic databases and reference lists of included SRs were searched. Eligible SRs were classified as having low, high or unclear RoB. Findings of SRs were synthesised and data from primary studies combined to relate ED to field of view (FOV) and operating potential (kV).
Seven SRs were included: three displayed low RoB, three high and one had unclear RoB. Only one SR related ED to image quality. Deficiencies in reporting of eligibility criteria, study selection and synthesis of results in SRs were identified. FOV height had a significant relationship with ED, explaining 27.2% of its variability. Median ED for three FOV categories differed significantly. Operating potential had a weak relationship with ED, with no significant difference in median ED between three operating potential groups.
The ROBIS tool should have a role for meta-reviews of different aspects of radiology. The disappointing results for RoB might be remedied by developing standards to improve the quality of reporting of primary dosimetry studies and of SRs. Future dosimetry studies should always relate ED to image quality or diagnostic accuracy.
This meta-review is the first to implement ROBIS for SRs of ED and identified that trustworthiness of some SRs is questionable. The percentage change in average ED per cm increase in FOV height could be calculated, emphasizing the importance of FOV as a determinant of ED in CBCT.
在一项关于口腔颌面锥形束 CT 有效剂量(ED)的元综述中,应用 ROBIS 工具评估系统评价(SR)的偏倚风险(RoB)。
检索了三个电子数据库和纳入 SR 的参考文献列表。将合格的 SR 分为 RoB 低、高或不明确。综合 SR 的结果,并结合原始研究的数据,将 ED 与视野(FOV)和操作电位(kV)联系起来。
共纳入 7 项 SR,其中 3 项显示 RoB 低,3 项显示 RoB 高,1 项显示 RoB 不明确。只有 1 项 SR 将 ED 与图像质量相关联。在 SR 中,发现了在纳入标准、研究选择和结果综合方面报告的不足。FOV 高度与 ED 有显著关系,可解释其变异性的 27.2%。三个 FOV 类别之间的 ED 中位数有显著差异。操作电位与 ED 有较弱的关系,三个操作电位组之间 ED 中位数无显著差异。
ROBIS 工具应在放射学不同方面的元综述中发挥作用。通过制定提高初级剂量学研究和 SR 报告质量的标准,可以改善 RoB 的结果。未来的剂量学研究应始终将 ED 与图像质量或诊断准确性相关联。
这是第一项针对 ED 的 SR 实施 ROBIS 的元综述,发现一些 SR 的可信度值得怀疑。可以计算出 FOV 高度每增加 1cm 时平均 ED 的平均变化百分比,这强调了 FOV 作为 CBCT 中 ED 决定因素的重要性。