Department for Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich (PUK), Switzerland; University Hospital Zurich, Switzerland; University Zurich, Switzerland.
Neurobiology Research Unit, University Hospital Rigshospitalet, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Biol Psychol. 2021 May;162:108117. doi: 10.1016/j.biopsycho.2021.108117. Epub 2021 May 13.
In recent medical research, tremendous progress has been made in the application of deep learning (DL) techniques. This article systematically reviews how DL techniques have been applied to electroencephalogram (EEG) data for diagnostic and predictive purposes in conducting research on mental disorders. EEG-studies on psychiatric diseases based on the ICD-10 or DSM-V classification that used either convolutional neural networks (CNNs) or long -short-term-memory (LSTMs) networks for classification were searched and examined for the quality of the information they contained in three domains: clinical, EEG-data processing, and deep learning. Although we found that the description of EEG acquisition and pre-processing was sufficient in most of the studies, we found, that many of them lacked a systematic characterization of clinical features. Furthermore, many studies used misguided model selection procedures or flawed testing. It is recommended that the study of psychiatric disorders using DL in the future must improve the quality of clinical data and follow state of the art model selection and testing procedures so as to achieve a higher research standard and head toward a clinical significance.
在最近的医学研究中,深度学习(DL)技术的应用取得了巨大的进展。本文系统地回顾了 DL 技术如何应用于脑电图(EEG)数据,以进行精神障碍的诊断和预测研究。基于 ICD-10 或 DSM-V 分类的精神病学疾病的 EEG 研究,使用卷积神经网络(CNN)或长短时记忆(LSTM)网络进行分类,对其在临床、EEG 数据处理和深度学习三个领域的信息质量进行了搜索和检查。虽然我们发现大多数研究都充分描述了 EEG 的采集和预处理,但我们发现,其中许多研究缺乏对临床特征的系统描述。此外,许多研究使用了误导性的模型选择程序或有缺陷的测试。建议未来使用 DL 研究精神障碍时,必须提高临床数据的质量,并遵循最先进的模型选择和测试程序,以达到更高的研究标准,并朝着临床意义迈进。