Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Joint Center for Neuroscience and Neural Engineering, Southern University of Science and Technology, Shenzhen, China.
Front Neural Circuits. 2021 Apr 30;15:633235. doi: 10.3389/fncir.2021.633235. eCollection 2021.
Neural circuits in the basolateral amygdala (BLA) play a pivotal role in the learning and memory formation, and processing of emotionally salient experiences, particularly aversive ones. A diverse population of GABAergic neurons present in the BLA orchestrate local circuits to mediate emotional memory functions. Targeted manipulation of GABAergic neuronal subtypes has shed light on cell-type specific functional roles in the fear learning and memory, revealing organizing principles for the operation of inhibitory circuit motifs in the BLA.
外侧杏仁核（BLA）中的神经回路在学习和记忆形成以及情绪相关经验的处理中起着关键作用，尤其是那些令人不快的经验。BLA 中存在的 GABA 能神经元的多样化群体协调局部回路以介导情绪记忆功能。靶向 GABA 能神经元亚型的操作揭示了恐惧学习和记忆中细胞类型特异性功能作用，揭示了 BLA 中抑制性回路模式运作的组织原则。
