Leigh T J, Bird H A, Hindmarch I, Wright V
Regional Rheumatology Centre, Royal Bath Hospital, Harrogate, North Yorkshire, UK.
Rheumatol Int. 1988;8(2):67-70. doi: 10.1007/BF00271837.
Nocturnal body motility has been compared in a sleep laboratory between patients with osteoarthritis and healthy age-, sex- and weight-matched controls using a Bio-medical timer and bedleg force transducers connected to a Disa polygraph. Four motility variables were derived (duration of movement; duration adjusted for sensitivity; number of movements; number of 30-s epochs containing movements) enabling an assessment of nocturnal body motility in the two groups. There was a trend for osteoarthritic patients to move more than controls during sleep on all variables measured, although this did not reach statistical significance. Temazepam elixir (0.4 mg/kg body weight/night) reduced all four motility variables in both osteoarthritic patients and controls, although only the reduction of the number of 30-s epochs containing movements (P less than 0.05) in the control group attained statistical significance.
在睡眠实验室中,使用连接到Disa多导记录仪的生物医学定时器和床腿力传感器,对骨关节炎患者与年龄、性别和体重匹配的健康对照者的夜间身体活动进行了比较。得出了四个活动变量(运动持续时间;根据敏感度调整后的持续时间;运动次数;包含运动的30秒时间段数量),从而能够评估两组患者的夜间身体活动情况。在所有测量变量上,骨关节炎患者在睡眠期间的活动趋势均比对照组多,尽管这未达到统计学显著性。替马西泮酏剂(0.4毫克/千克体重/晚)使骨关节炎患者和对照组的所有四个活动变量均减少,不过仅对照组中包含运动的30秒时间段数量的减少(P<0.05)达到了统计学显著性。