Li C C, Chakravarti A
Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261.
Am J Hum Genet. 1988 Aug;43(2):197-205.
There are two methods for calculating the posttests probability of paternity, viz., the nonexclusion probability method (E method) and the paternity index method (lambda method). This report reviews these two methods and explains the reasons behind them, in the hope that it might alleviate the current controversy between the advocates of these two methods. The emphasis throughout the paper is on exposition, using simple examples to illustrate certain principles or properties. A discussion follows the presentation of the two methods. The calculation of the paternity index is based on the genotype (or phenotype) of the accused man; and the value of the paternity index remains the same whether the accusation itself is true or false.
计算父权后验概率有两种方法,即非排除概率法(E法)和父权指数法(λ法)。本报告回顾了这两种方法并解释了其背后的原因,希望这可能缓解目前这两种方法支持者之间的争议。本文通篇重点在于阐述,使用简单示例来说明某些原理或特性。在介绍这两种方法之后进行了讨论。父权指数的计算基于被指控男子的基因型(或表型);无论指控本身是真是假,父权指数的值都保持不变。