Tesh R B, Chen W R, Catuccio D
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510.
Am J Trop Med Hyg. 1988 Jul;39(1):127-30. doi: 10.4269/ajtmh.1988.39.127.
The levels of albumin, IgG, IgM, and complement (C3) were determined by enzyme-linked immunosorbent assay in Aedes albopictus and Phlebotomus papatasi at regular intervals after feeding on human blood. Albumin disappeared most rapidly; by 48 hr, detectable levels of albumin had decreased 100-fold. In contrast, IgG and IgM survived longer and were still detectable at low levels several days after ingestion. C3 was intermediate in its rate of degradation. In general, serum protein disappearance occurred more rapidly in Ae. albopictus than in Ph. papatasi, despite a larger volume of blood ingested by the former.
通过酶联免疫吸附测定法,在白纹伊蚊和巴氏白蛉吸食人血后的定期时间点,测定白蛋白、IgG、IgM和补体(C3)的水平。白蛋白消失得最快;到48小时时,可检测到的白蛋白水平已下降了100倍。相比之下,IgG和IgM存活时间更长,摄入后数天仍可在低水平检测到。C3的降解速度处于中间水平。总体而言,尽管白纹伊蚊摄入的血量更多,但血清蛋白在白纹伊蚊中的消失速度比巴氏白蛉更快。