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股骨头坏死治疗的失败和进展至全髋关节置换术:贝叶斯网状Meta 分析。

Failure and progression to total hip arthroplasty among the treatments for femoral head osteonecrosis: a Bayesian network meta-analysis.

机构信息

Department of Orthopedics and Trauma Surgery, RWTH Aachen University Clinic, 52064 Aachen, Germany.

Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi SA, Italy.

出版信息

Br Med Bull. 2021 Jun 10;138(1):112-125. doi: 10.1093/bmb/ldab006.

Abstract

INTRODUCTION

Osteonecrosis of the femoral head (ONFH) often leads to secondary osteoarthritis and total hip arthroplasty.

SOURCE OF DATA

Recent published literatures.

AREAS OF AGREEMENT

There has been increasing focus on the early intervention in ONFH patients to preserve the native hip articulation, reduce pain and improve function.

AREAS OF CONTROVERSY

Efficacy of surgical strategies for ONFH is debated. Several clinical studies showed controversial results, and the best treatment has not yet been clarified.

GROWING POINTS

To provide an overview over current treatment options for ONFH compares their failure rates and conversion to total hip arthroplasty (THA) rates.

AREAS TIMELY FOR DEVELOPING RESEARCH

Core decompression (CD) augmented with autologous bone grafting plus the implantation of bone marrow concentrate can decrease the rate of failure and progression to THA rates compared to CD alone.

摘要

简介

股骨头坏死(ONFH)常导致继发性骨关节炎和全髋关节置换。

资料来源

近期发表的文献。

共识领域

人们越来越关注早期干预 ONFH 患者,以保留原生髋关节,减轻疼痛并改善功能。

争议领域

ONFH 的手术策略的疗效存在争议。几项临床研究显示出有争议的结果,最佳治疗方法尚未明确。

研究进展

提供 ONFH 目前治疗选择的概述,比较其失败率和转为全髋关节置换术(THA)的比率。

需要及时研究的领域

与单纯 CD 相比,CD 联合自体骨移植加骨髓浓缩物植入可降低失败率和进展为 THA 的比率。

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