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GSDMD 介导的心肌细胞细胞焦亡促进心肌缺血再灌注损伤。

GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury.

机构信息

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China (H.S., Y.G., Z.D., J.Y., X.L., S.Z., L.M., F.Z., K.H., A.S., J.G.).

NHC Key Laboratory of Viral Heart Diseases, Shanghai, China (H.S., Y.G., Z.D., J.Y., X.L., S.Z., L.M., F.Z., K.H., A.S., J.G.).

出版信息

Circ Res. 2021 Jul 23;129(3):383-396. doi: 10.1161/CIRCRESAHA.120.318629. Epub 2021 May 21.

DOI:10.1161/CIRCRESAHA.120.318629
PMID:34015941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8291144/
Abstract

[Figure: see text].

摘要

[图:见正文]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/b25b0cec2aee/res-129-383-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/1a3981b4afbc/res-129-383-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/714e5e6d8ba2/res-129-383-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/965715cdac2b/res-129-383-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/11412c969247/res-129-383-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/45ebfa2a4d6f/res-129-383-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/a12bc2eee012/res-129-383-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/90cbeca17ab0/res-129-383-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/b25b0cec2aee/res-129-383-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/1a3981b4afbc/res-129-383-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/714e5e6d8ba2/res-129-383-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/965715cdac2b/res-129-383-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/11412c969247/res-129-383-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/45ebfa2a4d6f/res-129-383-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/a12bc2eee012/res-129-383-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/90cbeca17ab0/res-129-383-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9986/8291144/b25b0cec2aee/res-129-383-g008.jpg

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Nat Rev Cardiol. 2020 Dec;17(12):773-789. doi: 10.1038/s41569-020-0403-y. Epub 2020 Jul 3.
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.细胞死亡的分子机制:细胞死亡命名委员会 2018 年的建议。
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MAFF mitigates oxidative stress and pyroptosis in cardiopulmonary bypass-induced myocardium injury.褪黑素减轻体外循环诱导的心肌损伤中的氧化应激和细胞焦亡。
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A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse Heart.一种从成年小鼠心脏中同时分离存活心肌细胞和非心肌细胞的简化的、无需Langendorff装置的方法。
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