Suppr超能文献

马拉维五岁以下儿童疟疾与贫血的联合建模

Joint modelling of malaria and anaemia in children less than five years of age in Malawi.

作者信息

Gaston Rugiranka Tony, Ramroop Shaun, Habyarimana Faustin

机构信息

School of Mathematics, Statistics and Computer Sciences, University of KwaZulu-Natal, Pietermaritzburg Campus, Private Bag X01, Scottsville, 3209, South Africa.

Health Economics and HIV/AIDS Research Division (HEARD), University of KwaZulu-Natal, Westville Campus, Private Bag X01, Westville, 3629, South Africa.

出版信息

Heliyon. 2021 May 4;7(5):e06899. doi: 10.1016/j.heliyon.2021.e06899. eCollection 2021 May.

Abstract

BACKGROUND

Malaria and anaemia jointly remain a public health problem in developing countries of which Malawi is one. Although there is an improvement along with intervention strategies in fighting against malaria and anaemia in Malawi, the two diseases remain significant problems, especially in children 6-59 months of age. The main objective of this study was to examine the association between malaria and anaemia. Moreover, the study investigated whether socio-economic, geographic, and demographic factors had a significant impact on malaria and anaemia.

DATA AND METHODOLOGY

The present study used a secondary cross-sectional data set from the 2017 Malawi Malaria Indicator Survey (MMIS) with a total number of 2 724 children 6-9 months of age. The study utilized a multivariate joint model within the ambit of the generalized linear mixed model (GLMM) to analyse the data. The two response variables for this study were: the child has either malaria or anaemia.

RESULTS

The prevalence of malaria was 37.2% of the total number of children who were tested using an RDT, while 56.9% were anaemic. The results from the multivariate joint model under GLMM indicated a positive association between anaemia and malaria. Furthermore, the same results showed that mother's education level, child's age, the altitude of the place of residence, place of residence, toilet facility, access to electricity and children who slept under a mosquito bed net the night before the survey had a significant effect on malaria and anaemia.

CONCLUSION

The study indicated that there is a strong association between anaemia and malaria. This is interpreted to indicate that controlling for malaria can result in a reduction of anaemia. The socio-economic, geographical and demographic variables have a significant effect on improving malaria and anaemia. Thus, improving health care, toilet facilities, access to electricity, especially in rural areas, educating the mothers of children and increasing mosquito bed nets would contribute in the reduction of malaria and anaemia in Malawi.

摘要

背景

疟疾和贫血仍是包括马拉维在内的发展中国家面临的公共卫生问题。尽管马拉维在抗击疟疾和贫血方面采取了干预策略并有所改善,但这两种疾病仍然是重大问题,尤其是在6至59个月大的儿童中。本研究的主要目的是检验疟疾与贫血之间的关联。此外,该研究还调查了社会经济、地理和人口因素是否对疟疾和贫血有重大影响。

数据与方法

本研究使用了2017年马拉维疟疾指标调查(MMIS)的二次横断面数据集,共有2724名6至9个月大的儿童。该研究在广义线性混合模型(GLMM)范围内使用多变量联合模型来分析数据。本研究的两个反应变量为:儿童患有疟疾或贫血。

结果

使用快速诊断测试(RDT)检测的儿童中,疟疾患病率为37.2%,而贫血患病率为56.9%。GLMM下多变量联合模型的结果表明贫血与疟疾之间存在正相关。此外,相同结果表明,母亲的教育水平、孩子的年龄、居住地点的海拔、居住地点、卫生设施、供电情况以及在调查前一晚睡在蚊帐下的儿童对疟疾和贫血有显著影响。

结论

该研究表明贫血与疟疾之间存在密切关联。这被解释为表明控制疟疾可导致贫血症减少。社会经济、地理和人口变量对改善疟疾和贫血有显著影响。因此,改善医疗保健、卫生设施、供电情况,特别是在农村地区,对儿童母亲进行教育并增加蚊帐数量,将有助于减少马拉维的疟疾和贫血症。

相似文献

1
Joint modelling of malaria and anaemia in children less than five years of age in Malawi.
Heliyon. 2021 May 4;7(5):e06899. doi: 10.1016/j.heliyon.2021.e06899. eCollection 2021 May.
2
Prevalence of and factors associated with malaria in children under five years of age in Malawi, using malaria indicator survey data.
Heliyon. 2020 May 13;6(5):e03946. doi: 10.1016/j.heliyon.2020.e03946. eCollection 2020 May.
8
Copula geoadditive modelling of anaemia and malaria in young children in Kenya, Malawi, Tanzania and Uganda.
J Health Popul Nutr. 2020 Nov 6;39(1):8. doi: 10.1186/s41043-020-00217-8.

引用本文的文献

1
Determinants of anemia among children under five in Eastern Uganda: a community-based cross-sectional study.
Front Public Health. 2025 Aug 13;13:1618395. doi: 10.3389/fpubh.2025.1618395. eCollection 2025.
8

本文引用的文献

2
Copula geoadditive modelling of anaemia and malaria in young children in Kenya, Malawi, Tanzania and Uganda.
J Health Popul Nutr. 2020 Nov 6;39(1):8. doi: 10.1186/s41043-020-00217-8.
3
Prevalence of and factors associated with malaria in children under five years of age in Malawi, using malaria indicator survey data.
Heliyon. 2020 May 13;6(5):e03946. doi: 10.1016/j.heliyon.2020.e03946. eCollection 2020 May.
5
Prevalence of inherited blood disorders and associations with malaria and anemia in Malawian children.
Blood Adv. 2018 Nov 13;2(21):3035-3044. doi: 10.1182/bloodadvances.2018023069.
6
Malaria in children under-five: A comparison of risk factors in lakeshore and highland areas, Zomba district, Malawi.
PLoS One. 2018 Nov 12;13(11):e0207207. doi: 10.1371/journal.pone.0207207. eCollection 2018.
7
Anaemia and malaria.
Malar J. 2018 Oct 19;17(1):371. doi: 10.1186/s12936-018-2509-9.
9
Prevalence and predictors of anemia among children under 5 years of age in Arusha District, Tanzania.
Pediatric Health Med Ther. 2018 Feb 5;9:9-15. doi: 10.2147/PHMT.S148515. eCollection 2018.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验