Division of Plastic Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN, USA.
Medical School, University of Minnesota, Minneapolis, MN, USA.
Breast J. 2021 Aug;27(8):671-674. doi: 10.1111/tbj.14242. Epub 2021 May 24.
There are increasing reports of autoimmune and dermatologic sequelae of COVID-19. We describe an otherwise healthy patient with recent history of serious COVID-19 infection who developed post-surgical pyoderma gangrenosum following bilateral reduction mammoplasty and was successfully treated with infliximab, mycophenolic acid, and corticosteroids. We present this case to highlight the lingering systemic proinflammatory effects of COVID-19 infection that may increase the risk of rare autoimmune complications of surgery. As a complete understanding of the long-term effects of COVID-19 is poorly understood, patients with a history of COVID-19 infection should be appropriately counseled to these possible risks when discussing surgery.
越来越多的报告显示 COVID-19 会引起自身免疫和皮肤后遗症。我们描述了一位原本健康的患者，近期有严重 COVID-19 感染史，在接受双侧乳房缩小术后发生手术后坏疽性脓皮病，并用英夫利昔单抗、霉酚酸酯和皮质类固醇成功治疗。我们提出这个病例是为了强调 COVID-19 感染的持续全身促炎作用可能会增加手术罕见自身免疫并发症的风险。由于对 COVID-19 感染的长期影响了解甚少，因此在讨论手术时，应向有 COVID-19 感染史的患者适当告知这些可能的风险。
