Talib Haider J, Mousa Hussein A, Mahmood Athraa A
Department of Periodontal Dentistry, College of Dentistry, Mustansiriyah University, Baghdad, Iraq.
J Int Soc Prev Community Dent. 2021 Apr 15;11(2):138-143. doi: 10.4103/jispcd.JISPCD_371_20. eCollection 2021 Mar-Apr.
The traditional manner of treatment of periodontal tissue inflammation includes giving information about the problem to the patient, oral motivation, and mechanical scaling and root planning (SRP).
We aimed at estimating the effect of using toothpaste with hyaluronic acid (Hyaluronan, HA) and xylitol (HAX) as a therapeutic agent in the treatment of plaque-induced gingivitis.
Sixty male patients who were in the age group of 20 to 35 years participated in this study. All of them endured 4 appointments, who suffered plaque-induced gingivitis, they distributed into 2 groups depending on the toothpaste variety: group 1 (G1): made up of 30 patients who consume toothpaste that contains HAX, while group 2 (G2): made up of 30 patients who consume toothpaste without HAX (placebo type). Clinical periodontal parameters (CPPs) for all of them were recorded, once at the beginning of the treatment besides four times throughout the treatment at weekly interims during all visits.
The means of plaque indices (PLI) and gingival indices (GI) decreased along with the sessions for both groups, where the initial means of PLI and GI (baseline) were 2.55 ± 0.14, 2.33 ± 0.15 for the G1, and 2.57 ± 0.13, 2.34 ± 0.16 for G2, respectively; whereas the least means shown at the fourth visit were 0.39 ± 0.05, 0.30 ± 0.06 for G1, and 0.71 ± 0.07, 0.61 ± 0.05 for G2, respectively. There was a reduction in the mean percent of bleeding on probing (BOP) score 1 for all visits in both groups. Finally, an intragroup comparison among dissimilar visits and intergroup comparisons for each visit showed highly significant differences at a -value of ≤ 0.001 for PLI, GI, and BOP.
Using toothpaste with or without HAX can decrease gingival inflammation; it can result in a higher improvement in the periodontal status of patients than toothpaste without HAX.
牙周组织炎症的传统治疗方式包括向患者说明问题、进行口腔宣教以及机械洁治和根面平整（SRP）。
我们旨在评估使用含透明质酸（HA）和木糖醇（HAX）的牙膏作为治疗剂在治疗菌斑性牙龈炎中的效果。
60名年龄在20至35岁之间的男性患者参与了本研究。他们均患有菌斑性牙龈炎，共接受4次就诊，根据牙膏种类分为2组：第1组（G1）：由30名使用含HAX牙膏的患者组成，而第2组（G2）：由30名使用不含HAX牙膏（安慰剂型）的患者组成。在治疗开始时以及所有就诊期间每周一次的4次治疗过程中，记录他们所有人的临床牙周参数（CPPs）。
两组的菌斑指数（PLI）和牙龈指数（GI）均值均随着治疗次数的增加而降低，其中G1组PLI和GI的初始均值（基线）分别为2.55±0.14、2.33±0.15，G2组分别为2.57±0.13、2.34±0.16；而在第4次就诊时显示的最低均值，G1组分别为0.39±0.05、0.30±0.06，G2组分别为0.71±0.07、0.61±0.05。两组在所有就诊时探诊出血（BOP）评分为1的平均百分比均有所降低。最后，不同就诊间的组内比较以及每次就诊的组间比较显示，PLI、GI和BOP在α值≤0.001时存在高度显著差异。
使用含或不含HAX的牙膏均可减轻牙龈炎症；与不含HAX的牙膏相比，它能使患者的牙周状况得到更大改善。
