PneumoCardioVascular Lab/HUOL, Hospital Universitário Onofre Lopes, Empresa Brasileira de Serviços Hospitalares (EBSERH), Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Departamento de Fisioterapia, Laboratório de Inovação Tecnológica em Reabilitação, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
PLoS One. 2021 May 26;16(5):e0252150. doi: 10.1371/journal.pone.0252150. eCollection 2021.
Sniff nasal inspiratory pressure (SNIP) is a voluntary inspiratory maneuver measured through a plug occluding one nostril. The investigation of the number of maneuvers necessary to reach the highest peak of SNIP in pediatric populations has been inconsistent. Thus, this study aimed to assess the reliability of SNIP in healthy children aged 6 to 11 years according to sex and age group, and to determine the optimal number of SNIP maneuvers for this age group.
This cross-sectional study included healthy children with normal pulmonary function. We performed 12 to 20 SNIP maneuvers, with a 30 s rest between each maneuver. The reliability was tested using the intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis for agreement.
A total of 121 healthy children (62 girls [51%]) were included in this study. The ICC and corresponding confidence interval (CI) between the highest measure and the first reproducible maneuver were 0.752 (0.656-0.824), SEM = 10.37 cmH2O, and MDC = 28.74 cmH2O. For children aged 6 to 7 years, the ICC was 0.669 (0.427-0.822), SEM = 10.76 cmH2O and MDC = 29.82 cmH2O; for children aged 8 to 11 years, the ICC was 0.774 (0.662-0.852), SEM = 9.74 cmH2O, and MDC = 26.05 cmH2O. For girls, the ICC was 0.817 (0.706-0.889), SEM = 9.40 cmH2O and MDC = 26.05 cmH2O; for boys, the ICC was 0.671 (0.487-0.798), SEM = 11.51 cmH2O, and MDC = 31.90 cmH2O. Approximately 80% of the total sample reached the highest SNIP before the 10th maneuver.
SNIP demonstrated moderate reliability between the maneuvers in children aged 6 to 11 years; older children and girls reached the SNIP peak faster. Finally, results indicated that 12 maneuvers were sufficient for healthy children aged 6 to 11 years to achieve the highest SNIP peak.
嗅吸鼻吸气压力（SNIP）是一种通过堵塞一个鼻孔来测量的自愿吸气动作。在儿科人群中，达到 SNIP 最高峰值所需的动作次数的研究结果并不一致。因此，本研究旨在根据性别和年龄组评估健康 6 至 11 岁儿童的 SNIP 的可靠性，并确定该年龄组的最佳 SNIP 动作次数。
这是一项横断面研究，纳入了肺功能正常的健康儿童。我们进行了 12 至 20 次 SNIP 动作，每个动作之间休息 30 秒。使用组内相关系数（ICC）、测量标准误差（SEM）、最小可检测变化（MDC）和 Bland-Altman 分析评估一致性，以测试可靠性。
共有 121 名健康儿童（62 名女孩[51%]）纳入本研究。最高测量值与第一次可重复动作之间的 ICC 和相应置信区间（CI）为 0.752（0.656-0.824），SEM 为 10.37cmH2O，MDC 为 28.74cmH2O。对于 6 至 7 岁的儿童，ICC 为 0.669（0.427-0.822），SEM 为 10.76cmH2O，MDC 为 29.82cmH2O；对于 8 至 11 岁的儿童，ICC 为 0.774（0.662-0.852），SEM 为 9.74cmH2O，MDC 为 26.05cmH2O。对于女孩，ICC 为 0.817（0.706-0.889），SEM 为 9.40cmH2O，MDC 为 26.05cmH2O；对于男孩，ICC 为 0.671（0.487-0.798），SEM 为 11.51cmH2O，MDC 为 31.90cmH2O。大约 80%的总样本在第 10 次动作前达到了最高的 SNIP。
SNIP 在 6 至 11 岁儿童中表现出动作之间的中等可靠性；年龄较大的儿童和女孩更快达到 SNIP 峰值。最后，结果表明，对于 6 至 11 岁的健康儿童，进行 12 次动作即可达到最高 SNIP 峰值。
