Kamran S, Bakshi R
Dent Neurologic Institute, Department of Neurology, Millard Fillmore Health System, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, 14209, USA.
Neuroradiology. 1998 Aug;40(8):519-21. doi: 10.1007/s002340050637.
MRI may be helpful in showing brain toxicity associated with chronic toluene inhalation. We report clinical and MRI findings over 3 years in a man with gradual neurologic decline secondary to toluene abuse. Cerebral atrophy most prominently involved the corpus callosum and cerebellar vermis. On T2-weighted images, loss of gray-white matter contrast, diffuse supratentorial white matter high-signal lesions, and low signal in the basal ganglia and midbrain were seen. In addition, MRI showed abnormal labor cortical low signal on T2-weighted images, most prominent in the primary motor and visual cortex. This cortical T2 shortening, not previously described in this condition, may reflect iron deposition.
磁共振成像（MRI）可能有助于显示与慢性吸入甲苯相关的脑毒性。我们报告了一名因甲苯滥用继发渐进性神经功能衰退的男性患者在3年期间的临床及MRI检查结果。脑萎缩最显著地累及胼胝体和小脑蚓部。在T2加权图像上，可见灰白质对比度丧失、幕上弥漫性白质高信号病变以及基底节和中脑低信号。此外，MRI显示在T2加权图像上脑皮质低信号异常，在初级运动皮质和视觉皮质最为明显。这种皮质T2缩短在该病症中此前未见报道，可能反映了铁沉积。
