Yoon Jennifer, Hu Steve, Farrell Jessica, Shah Kandarp K, Chintanaboina Jaya Krishna
Internal Medicine, University of California San Francisco Fresno, Fresno, USA.
Gastroenterology and Hepatology, University of California San Francisco Fresno, Fresno, USA.
Cureus. 2021 Apr 20;13(4):e14599. doi: 10.7759/cureus.14599.
Testicular choriocarcinomas comprise less than 1% of all testicular tumors and are often highly vascular with early hematogenous metastasis. Choriocarcinoma syndrome (CS) is a rare entity distinguished by diffuse tumor burden and often fatal bleeding from metastatic sites. Most reported cases describe pulmonary hemorrhage secondary to initiation of chemotherapy. We present a fatal case of a young, previously healthy male with overwhelming gastrointestinal bleeding as the presenting sign of CS. Our case demonstrates that CS should be considered in the differential diagnosis for refractory anemia due to gastrointestinal hemorrhage in a young male with a testicular mass.
睾丸绒毛膜癌占所有睾丸肿瘤的比例不到1%，通常血管丰富，早期即可发生血行转移。绒毛膜癌综合征（CS）是一种罕见的病症，其特征为肿瘤广泛播散，且转移部位常发生致命性出血。大多数报道的病例描述的是化疗开始后继发的肺出血。我们报告了一例年轻、既往健康男性的致命病例，该患者以严重的胃肠道出血为CS的首发症状。我们的病例表明，对于患有睾丸肿块的年轻男性，因胃肠道出血导致难治性贫血时，鉴别诊断应考虑CS。
