The College of Chemistry and Chemical Engineering, Yangzhou University, 180 Si-Wang-Ting Road, Yangzhou, 225002, P. R. China.
Centre for Clean Energy Technology, School of Chemistry and Forensic Science, Mathematical and Physical Science, University of Technology Sydney, City Campus, Broadway, Sydney, NSW 2007, Australia.
Chem Asian J. 2021 Jul 19;16(14):1949-1955. doi: 10.1002/asia.202100332. Epub 2021 Jun 7.
We discovered that the 2D Ti C T MXene sheet displays an ultra-high removal capability for bilirubin (BR). In particular, MXene shows 47.6 times higher removal efficiency over traditional activated carbon absorbents. The effect of MXene on the removal rate of BR in BR solution containing different concentrations of bovine serum albumin (BSA) was studied. The adsorption capacity of BSA for BR at high concentration of 5 g L was about 85% of the best adsorption capacity. The MXene before and after adsorption was characterized by SEM, FT-IR and XPS. Furthermore, MXene beads were prepared, and the hemoperfusion simulation experiment was carried out. The results show that the adsorption capacity of MXene for bilirubin can reach 1192.9 mg g . This study suggests that MXene may be promising in the treatment of hyperbilirubinemia.
我们发现二维 TiC T MXene 薄片对胆红素 (BR) 具有超高的去除能力。特别是，MXene 对传统活性炭吸附剂的去除效率高出 47.6 倍。研究了 MXene 对含有不同浓度牛血清白蛋白 (BSA) 的 BR 溶液中 BR 去除率的影响。在 5 g/L 的高浓度下，BSA 对 BR 的吸附容量约为最佳吸附容量的 85%。通过 SEM、FT-IR 和 XPS 对吸附前后的 MXene 进行了表征。此外，还制备了 MXene 珠，并进行了血液灌流模拟实验。结果表明，MXene 对胆红素的吸附容量可达 1192.9 mg/g。这项研究表明，MXene 在高胆红素血症的治疗中可能具有广阔的应用前景。
