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Quantitative proteomic biomarkers from extracellular vesicles of human seminal plasma in the differential diagnosis of azoospermia.

作者信息

Yao Liping, Guo Yueshuai, Zhang Xiangzheng, Xu Chen, Wang Yichun, Liu Xiaofei, Wang Yue, Li Yan, Qi Yaling, Sha Jiahao, Qin Chao, Yang Xiaoyu, Guo Xuejiang

机构信息

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.

Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

出版信息

Clin Transl Med. 2021 May;11(5):e423. doi: 10.1002/ctm2.423.

DOI:10.1002/ctm2.423
PMID:34047465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8161617/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/ca69b9a09146/CTM2-11-e423-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/5d6bd24ed797/CTM2-11-e423-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/debc3de6120e/CTM2-11-e423-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/e599d329def0/CTM2-11-e423-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/ca69b9a09146/CTM2-11-e423-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/5d6bd24ed797/CTM2-11-e423-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/debc3de6120e/CTM2-11-e423-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/e599d329def0/CTM2-11-e423-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8780/8161617/ca69b9a09146/CTM2-11-e423-g001.jpg

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J Extracell Vesicles. 2020 Mar 11;9(1):1736935. doi: 10.1080/20013078.2020.1736935. eCollection 2020.
2
Evaluation of the azoospermic male: a committee opinion.男性不育评估：专家共识。
Fertil Steril. 2018 May;109(5):777-782. doi: 10.1016/j.fertnstert.2018.01.043.
3
Exosomal microRNAs in seminal plasma are markers of the origin of azoospermia and can predict the presence of sperm in testicular tissue.
STYXL1 调控 CCT 复合物组装和精子形成中的鞭毛微管蛋白折叠。
Nat Commun. 2024 Jan 2;15(1):44. doi: 10.1038/s41467-023-44337-1.
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