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BENviewer:基于图嵌入模型的基因交互网络可视化服务器。

BENviewer: a gene interaction network visualization server based on graph embedding model.

机构信息

State Key Laboratory of Bioelectronics, Southeast University, Sipailou No.2, Nanjing, Jiangsu 210096, China.

出版信息

Database (Oxford). 2021 May 28;2021. doi: 10.1093/database/baab033.

Abstract

BENviewer is a brand-new online gene interaction network visualization server based on graph embedding models. With mature graph embedding algorithms applied on several interaction network databases, it provides human-friendly 2D visualization based on more than 2000 biological pathways, and these results present not only genes involved but also tightness of interactions in an intuitive way. As a unique visualization server introducing graph embedding application for the first time, it is expected to help researchers gain deeper insights into biological networks beyond generating results explainable by existing knowledge. Additionally, operation flow for users is simplified to greater extent in its current version; meanwhile URL optimization contributes to data acquisition in batch for further analysis. BENviewer is freely available at http://www.bmeonline.cn/BENviewer, besides it is open-sourced at https://github.com/SKLB-lab/BENviewer, http://benviewer.bmeonline.cn.

摘要

BENviewer 是一个全新的基于图嵌入模型的在线基因交互网络可视化服务器。该服务器应用成熟的图嵌入算法于多个交互网络数据库,基于 2000 多个生物途径提供了人性化的 2D 可视化,不仅呈现了相关基因,还直观地展示了相互作用的紧密程度。作为首次引入图嵌入应用的独特可视化服务器,它有望帮助研究人员深入了解生物网络,超越现有知识可解释的结果。此外,在当前版本中,用户的操作流程得到了极大简化;同时,URL 优化有助于进行批量数据获取,以进行进一步分析。BENviewer 可免费在 http://www.bmeonline.cn/BENviewer 获取,此外,它还在 https://github.com/SKLB-lab/BENviewer、http://benviewer.bmeonline.cn 开源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5de1/8163240/d191d761d459/baab033f1.jpg

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