Department of Orthodontics, University Medicine Greifswald, Fleischmannstraße 42-44, 17475, Greifswald, Germany.
Department of Prosthetic Dentistry, Gerodontology and Biomaterials, University Medicine Greifswald, Fleischmannstraße 42-44, 17475, Greifswald, Germany.
Clin Oral Investig. 2022 Jan;26(1):353-364. doi: 10.1007/s00784-021-04006-3. Epub 2021 May 29.
Cephalometric analyses using lateral craniofacial radiographs are common diagnostic procedures for evaluating skeletal patterns. However, in patients with pronounced abnormalities like cleft lip and palate, standard cephalometric analyses and landmarks may not be suitable. This study aims to clarify whether the inclusion of landmarks less compromised by the cleft defect or located outside the cleft area results in a different cephalometric assessment of the viscerocranium. Delaire's whole-skull analysis and Bergen analysis were examined for similarities and underlying common observations.
MATERIALS/METHODS: Based on the cephalometric evaluation of 217 patients with different types of non-syndromal cleft formation, Delaire and Bergen analysis were compared using three statistical methods: correlation analysis, factor analysis, and cluster analysis. Reproducibility was assessed by Bland-Altman plots, intraclass correlation coefficients, mean absolute differences, and coefficients of variability.
Although Delaire analysis and Bergen analysis are based on different concepts and landmarks, a majority of corresponding variables was found. Certain aspects of craniofacial base relation and craniospinal articulation are only assessed by Delaire analysis. All but one variable showed very good reproducibility.
The inclusion of landmarks less compromised by or located outside the cleft area does not result in variables that provide a different assessment of the viscerocranial area.
The findings contradict the concept of invalidity of landmarks compromised by the cleft defect or located within the affected cleft area. Within the scope of its viscerocranial field of view, Bergen analysis appears to be on a par with Delaire analysis in the diagnosis of cleft patients.
使用侧颅面射线照相进行头影测量分析是评估骨骼模式的常见诊断程序。然而，在唇腭裂等明显畸形的患者中，标准的头影测量分析和标志点可能不适用。本研究旨在阐明是否包括受裂隙缺陷影响较小的标志点或位于裂隙区域外的标志点，会导致对内脏颅的头影测量评估结果不同。检查了 Delaire 全颅骨分析和 Bergen 分析的相似性和潜在的共同观察。
材料/方法：基于对 217 例不同类型非综合征性唇裂形成患者的头影测量评估，使用三种统计方法（相关分析、因子分析和聚类分析）比较了 Delaire 和 Bergen 分析：相关性分析、因子分析和聚类分析。通过 Bland-Altman 图、组内相关系数、平均绝对差异和变异系数评估可重复性。
尽管 Delaire 分析和 Bergen 分析基于不同的概念和标志点，但发现了大多数对应的变量。颅颌面基础关系和颅脊柱关节的某些方面仅通过 Delaire 分析进行评估。除一个变量外，所有变量的可重复性均非常好。
纳入受裂隙缺陷影响较小或位于裂隙区域外的标志点，不会导致对内脏颅区域评估不同的变量。在其内脏颅视野范围内，Bergen 分析在诊断唇腭裂患者方面似乎与 Delaire 分析相当。
这些发现与受裂隙缺陷影响或位于受影响的裂隙区域内的标志点无效的概念相矛盾。在其内脏颅视野范围内，Bergen 分析在诊断唇腭裂患者方面似乎与 Delaire 分析相当。
