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关于[具体内容]在人类疾病中的治疗潜力的叙述性综述。 (原文中“of”后面缺少具体内容)

A Narrative Review on Therapeutic Potentials of in Human Disorders.

作者信息

Panahi Kokhdan Esmaeel, Khodabandehloo Hadi, Ghahremani Hossein, Doustimotlagh Amir Hossein

机构信息

Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

Department of Clinical Biochemistry, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

出版信息

Evid Based Complement Alternat Med. 2021 May 7;2021:5516450. doi: 10.1155/2021/5516450. eCollection 2021.

Abstract

() is an aquatic vegetable that belongs to the Brassicaceae family, and it often grows near water. In traditional medicine, is a known remedy for hypercholesterolemia, hyperglycemia, hypertension, arthritis, bronchitis, diuresis, odontalgia, and scurvy. It also acts as an antiestrogenic and can be used as a nutritional supplement. It has been reported that these therapeutic effects are due to primary metabolites such as isothiocyanates, glucosinolates, polyphenols (flavonoids, phenolic acids, and proanthocyanidins), vitamins (B, B, B, B, E, and C), terpenes (including carotenoids), and bioelements which exist in this plant. Many pharmacological studies confirm the antioxidant, antibacterial, anticancer, antipsoriatic, anti-inflammatory, cardioprotective, renoprotective, hepatoprotective, and antigenotoxicity effects of . The consumption of extract can be useful in reducing the complications of hypercholesterolemia and hyperglycemia. Furthermore, the extract of could markedly augment the antioxidant enzymes such as superoxide dismutase and catalase activity. Interestingly, consumption of food rich in polyphenols such as extract can help reduce oxidative stress, DNA damage, and cancer susceptibility. Several studies also showed that extract significantly reduced liver injury as a result of cholestatic hepatic injury, gamma radiation, arsenic, and acetaminophen-induced hepatotoxicity. In this review, the researchers focus on the phytochemical and biochemical characterizations of and its therapeutic effects in the treatment of human diseases.

摘要

()是一种属于十字花科的水生蔬菜,通常生长在水边。在传统医学中,()是治疗高胆固醇血症、高血糖、高血压、关节炎、支气管炎、利尿、牙痛和坏血病的已知药物。它还具有抗雌激素作用,可用作营养补充剂。据报道,这些治疗作用归因于该植物中存在的初级代谢产物,如异硫氰酸盐、硫代葡萄糖苷、多酚(黄酮类、酚酸和原花青素)、维生素(B族、E和C)、萜类(包括类胡萝卜素)和生物元素。许多药理学研究证实了()的抗氧化、抗菌、抗癌、抗银屑病、抗炎、心脏保护、肾脏保护、肝脏保护和抗基因毒性作用。食用()提取物有助于减少高胆固醇血症和高血糖的并发症。此外,()提取物可显著增强超氧化物歧化酶和过氧化氢酶等抗氧化酶的活性。有趣的是,食用富含多酚的食物,如()提取物,有助于减轻氧化应激、DNA损伤和癌症易感性。几项研究还表明,()提取物可显著减轻胆汁淤积性肝损伤、γ射线、砷和对乙酰氨基酚诱导的肝毒性所致的肝损伤。在这篇综述中,研究人员重点关注了()的植物化学和生化特性及其在治疗人类疾病中的治疗作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23eb/8123986/0139b2753414/ECAM2021-5516450.001.jpg

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