Chouteau M, Namerow P B, Leppert P
Department of Obstetrics and Gynecology, St. Luke's/Roosevelt Hospital Center, New York, New York.
Obstet Gynecol. 1988 Sep;72(3 Pt 1):351-4.
A retrospective study of 343 women who lacked prenatal care was conducted to ascertain the effect of recent cocaine abuse on birth weight and gestational age. All pregnant women admitted in labor to a large urban teaching hospital between January 1 and December 31, 1986 who had not received prenatal care were included. The charts of these women were evaluated to obtain information about medical and obstetric complications of pregnancy, labor and delivery, and birth weight and gestational age of the infant. Information about drug use was obtained by urine toxicology at the time of admission. Results of ordinary least-squares multiple regression analyses indicated cocaine abuse to be a significant predictor of low birth weight and early gestational age. No correlation was found between cocaine abuse and abruptio placentae or maternal hypertension.
对343名未接受产前护理的女性进行了一项回顾性研究，以确定近期可卡因滥用对出生体重和孕周的影响。纳入了1986年1月1日至12月31日期间在一家大型城市教学医院分娩入院且未接受产前护理的所有孕妇。评估这些女性的病历，以获取有关妊娠、分娩和产程中的医学和产科并发症以及婴儿出生体重和孕周的信息。入院时通过尿液毒理学获取药物使用信息。普通最小二乘多元回归分析结果表明，可卡因滥用是低出生体重和孕周提前的重要预测因素。未发现可卡因滥用与胎盘早剥或母亲高血压之间存在相关性。
