Zhou Yaxin, Feng Yuan, Zhang Wei, Li Hongxia, Zhang Kui, Wu Zhenbiao
Department of Clinical Immunology, Xijing Hospital, Air Force Medical University (Fourth Military Medical University), Xi'an, China.
Department of Rheumatology and Immunology, Tangdu Hospital, Air Force Medical University (Fourth Military Medical University), Xi'an, China.
Front Cardiovasc Med. 2021 May 12;8:603354. doi: 10.3389/fcvm.2021.603354. eCollection 2021.
Takayasu arteritis (TA) is a kind of large-vessel vasculitis that mainly affects the aorta and its branches, and the patients are usually women at a relatively young age. The chronic inflammation of arteries in TA patients leads to stenosis, occlusion, dilatation, or aneurysm formation. Patients with TA thereby have a high risk of cardiovascular disease (CVD) complications, which are the most common cause of mortality. This review summarizes the main cardiovascular complications and the risk factors of cardiovascular complications in patients with TA. Here, we discuss the benefits and potential risks of physical exercise in patients with TA and give recommendations about exercise prescription for TA patients to decrease the risks of CVD and facilitate rehabilitation of cardiovascular complications, which might maximally improve the outcomes.
高安动脉炎（TA）是一种主要累及主动脉及其分支的大血管血管炎，患者通常为相对年轻的女性。TA患者动脉的慢性炎症会导致狭窄、闭塞、扩张或动脉瘤形成。因此，TA患者发生心血管疾病（CVD）并发症的风险很高，这是最常见的死亡原因。本综述总结了TA患者主要的心血管并发症以及心血管并发症的危险因素。在此，我们讨论TA患者体育锻炼的益处和潜在风险，并给出TA患者运动处方的建议，以降低CVD风险并促进心血管并发症的康复，这可能会最大程度地改善预后。
