Laboratório de Ecologia Vegetal, Universidade Regional Do Cariri, Departamento de Ciências Biológicas, 63105-000, Crato, CE, Brazil.
Laboratório de Pesquisa de Produtos Naturais, Universidade Regional Do Cariri, Departamento de Química Biológica, 63105-000, Crato, CE, Brazil.
J Ethnopharmacol. 2021 Oct 5;278:114248. doi: 10.1016/j.jep.2021.114248. Epub 2021 May 28.
Brazilian medicinal species of the Psidium genus are rich in secondary metabolites such as terpenes and phenolic compounds and present biological activities for several human diseases. For the native Psidium species, there are no specific research reports for any member of the genus about ethnobotanical research, hindering the joint analysis of its therapeutic indications together with the scientific evidence already investigated.
Analyze the therapeutic indications, the main chemical constituents, and the biological activities of native species of the Psidium to Brazil.
Systematic research was carried out in the Scopus, ScienceDirect, PubMed, and Web of Science databases over a period of ten years. Articles in English, Portuguese and Spanish were used. The research was divided into three phases, seeking information on ethnobotany, chemical composition and biological activities. The words were combined to structure the descriptors used in the search.
A total of 13 native species belonging to the Psidium genus were identified in this analysis, Psidium acutangulum DC., Psidium brownianum Mart. ex DC., Psidium cattleyanum Sabine, Psidium densicomum Mart. ex DC., Psidium grandifolium Mart. ex DC., Psidium guineense Sw., Psidium laruotteanum Cambess., Psidium myrsinites DC, Psidium myrtoides O. Berg, Psidium salutare (Kunth) O. Berg, Psidium schenckianum Kiaersk., Psidium sobralianum Proença & Landrum, Psidium striatulum Mart. ex DC. Of these, six were indicated in folk medicine, digestive system disorders being their main therapeutic indication. Most species presented an investigation of chemical composition and biological activity. They are rich in phenolic compounds, flavonoids, and terpenes and have antimicrobial, antioxidant, antiproliferative, and repellent activities.
Native species of the Psidium genus are important sources of active ingredients in combating adversities that affect the human health, especially regarding the digestive system. They have a rich chemical composition, responsible for the biological activities demonstrated for the species.
巴西桃金娘科植物 Psidium 属的药用物种富含萜类和酚类化合物等次生代谢产物，具有多种人类疾病的生物活性。对于本地 Psidium 物种，关于该属的任何成员都没有特定的研究报告涉及民族植物学研究，这阻碍了其治疗适应症与已经调查的科学证据的联合分析。
分析巴西本地 Psidium 物种的治疗适应症、主要化学成分和生物活性。
在 Scopus、ScienceDirect、PubMed 和 Web of Science 数据库中进行了为期十年的系统研究。使用了英语、葡萄牙语和西班牙语的文章。研究分为三个阶段，分别是寻找民族植物学、化学组成和生物活性方面的信息。使用的词组合结构了搜索中使用的描述符。
本分析共确定了 13 种属于 Psidium 属的本地物种，分别为 Psidium acutangulum DC.、Psidium brownianum Mart. ex DC.、Psidium cattleyanum Sabine、Psidium densicomum Mart. ex DC.、Psidium grandifolium Mart. ex DC.、Psidium guineense Sw.、Psidium laruotteanum Cambess.、Psidium myrsinites DC.、Psidium myrtoides O. Berg.、Psidium salutare (Kunth) O. Berg.、Psidium schenckianum Kiaersk.、Psidium sobralianum Proença & Landrum.、Psidium striatulum Mart. ex DC. 其中，有 6 种在民间医学中有应用，消化系统疾病是其主要治疗适应症。大多数物种都进行了化学成分和生物活性的研究。它们富含酚类化合物、类黄酮和萜类化合物，具有抗菌、抗氧化、抗增殖和驱虫活性。
Psidium 属的本地物种是对抗影响人类健康的不利因素的有效成分的重要来源，特别是针对消化系统。它们具有丰富的化学成分，这是其生物活性的原因。
