Serdar Eymirli Pınar, Eymirli Ayhan, Uzunoğlu Özyürek Emel
Department of Pediatric Dentistry, Faculity of Dentisry, Hacettepe University, Altındağ/Ankara, Turkey.
Department of Endodontics, Faculity of Dentisry, Hacettepe University, Altındağ/Ankara, Turkey.
Aust Endod J. 2021 Dec;47(3):616-623. doi: 10.1111/aej.12532. Epub 2021 Jun 1.
The effect of different medicaments and irrigation solutions on root dentin microhardness (MH) was evaluated depending on time. After initial measurements, MH of 60 maxillary incisors (n = 15 per group) was measured after 3 steps: irrigation with 2.5% sodium hypochlorite, exposure to medicaments [triple antibiotic (TAP) or calcium hydroxide (CH) pastes, 1 week or 1 month)] and final irrigation [20 mL of 17% EDTA or 20 mL 1% phytic acid (PA)]. The percentage of MH reduction was calculated. Data were analysed statistically at P < 0.05. Treatments caused a significant decrease in MH values compared to baseline and pre-measurements (P < 0.05). TAP significantly reduced the MH values of the samples over time (P < 0.05). Removal of TAP after 1 month with PA resulted in a significant reduction in MH compared to removing TAP after 1 week and CH removing after 1 month (P < 0.05). Considering the chemical preparation steps, the most hazardous effect on MH was observed after the first irrigation.
根据时间评估不同药物和冲洗液对牙根牙本质显微硬度（MH）的影响。在初始测量后，对60颗上颌切牙（每组n = 15）的MH进行三步测量：用2.5%次氯酸钠冲洗、接触药物[三联抗生素（TAP）或氢氧化钙（CH）糊剂，1周或1个月]以及最后冲洗[20 mL 17%乙二胺四乙酸（EDTA）或20 mL 1%植酸（PA）]。计算MH降低的百分比。在P < 0.05水平进行统计学分析。与基线和测量前相比，各处理均导致MH值显著降低（P < 0.05）。随着时间推移，TAP显著降低了样本的MH值（P < 0.05）。与1周后去除TAP以及1个月后去除CH相比，1个月后用PA去除TAP导致MH显著降低（P < 0.05）。考虑化学预备步骤，首次冲洗后观察到对MH的危害最大。
