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超声在个体化肉毒毒素治疗颈肌张力障碍中的作用。

The Role of Ultrasound for the Personalized Botulinum Toxin Treatment of Cervical Dystonia.

机构信息

Department of Neurology, Ludwig-Maximilians-University, 81377 Munich, Germany.

Department of Neurology and Clinical Neurophysiology, Schön Klinik München Schwabing, 80804 Munich, Germany.

出版信息

Toxins (Basel). 2021 May 20;13(5):365. doi: 10.3390/toxins13050365.

DOI:10.3390/toxins13050365
PMID:34065541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8161276/
Abstract

The visualization of the human body has frequently been groundbreaking in medicine. In the last few years, the use of ultrasound (US) imaging has become a well-established procedure for botulinum toxin therapy in people with cervical dystonia (CD). It is now undisputed among experts that some of the most relevant muscles in this indication can be safely injected under visual US guidance. This review will explore the method from basic technical considerations, current evidence to conceptual developments of the phenomenology of cervical dystonia. We will review the implications of introducing US to our understanding of muscle function and anatomy of common cervical dystonic patterns. We suggest a flow chart for the use of US to achieve a personalized treatment of people with CD. Thus, we hope to contribute a resource that is useful in clinical practice and that stimulates the ongoing development of this valuable technique.

摘要

人体可视化在医学中经常具有开创性。在过去的几年中,超声(US)成像的使用已成为治疗颈部肌张力障碍(CD)患者肉毒毒素治疗的成熟程序。现在,专家们一致认为,在这种情况下,可以在视觉超声引导下安全地注射一些最相关的肌肉。本综述将从基本技术考虑因素、当前证据到颈部肌张力障碍现象学的概念发展来探讨该方法。我们将回顾将 US 引入我们对常见颈部肌张力障碍模式的肌肉功能和解剖理解的影响。我们建议使用 US 为 CD 患者制定个性化治疗的流程图。因此,我们希望为临床实践提供有用的资源,并激发这项有价值技术的持续发展。

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Ergonomic Recommendations in Ultrasound-Guided Botulinum Neurotoxin Chemodenervation for Spasticity: An International Expert Group Opinion.超声引导肉毒毒素化学神经切断术治疗痉挛的人体工效学建议:国际专家小组意见。
Toxins (Basel). 2021 Mar 31;13(4):249. doi: 10.3390/toxins13040249.
2
Accuracy of non-guided versus ultrasound-guided injections in cervical muscles: a cadaver study.非引导与超声引导下颈椎肌肉注射的准确性:尸体研究。
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Dystonia and Tremor: A Cross-Sectional Study of the Dystonia Coalition Cohort.
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Tremor Other Hyperkinet Mov (N Y). 2025 Jan 17;15:3. doi: 10.5334/tohm.966. eCollection 2025.
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Treatment with OnabotulinumtoxinA for Oromandibular Dystonia: A Systematic Review and Meta-Analysis.奥曲肽治疗口下颌肌张力障碍的系统评价和荟萃分析
Toxins (Basel). 2024 Dec 16;16(12):546. doi: 10.3390/toxins16120546.
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Ultrasonography for Assessment and Intervention With Botulinum Toxin Injection for Tremors.超声检查在肉毒杆菌毒素注射治疗震颤的评估与干预中的应用
Ann Rehabil Med. 2024 Dec;48(6):396-404. doi: 10.5535/arm.240065. Epub 2024 Dec 16.
6
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Toxins (Basel). 2024 Nov 3;16(11):474. doi: 10.3390/toxins16110474.
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Self-perceived preparedness for practice among graduating physical medicine & rehabilitation residents.毕业的物理医学与康复住院医师对临床实践的自我认知准备情况。
PM R. 2025 Jan;17(1):24-31. doi: 10.1002/pmrj.13246. Epub 2024 Nov 19.
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J Neural Transm (Vienna). 2018 Jul;125(7):1037-1042. doi: 10.1007/s00702-018-1866-4. Epub 2018 Feb 27.