Huang Hsiu-Ju, Lee Chih-Wei, Li Tse-Hsi, Hsieh Tsung-Cheng
Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.
Department of Physical Therapy, Tzu Chi University, Hualien 97004, Taiwan.
Int J Environ Res Public Health. 2021 May 22;18(11):5558. doi: 10.3390/ijerph18115558.
This cross-sectional study aimed to investigate the difference in ranking of risk factors of onset age of acute myocardial infarction (AMI) between urban and rural areas in Eastern Taiwan. Data from 2013 initial onset of AMI patients living in the urban areas (n = 1060) and rural areas (n = 953) from January 2000 to December 2015, including onset age, and conventional risk factors including sex, smoking, diabetes, hypertension, dyslipidemia, and body mass index (BMI). The results of multiple linear regressions analysis showed smoking, obesity, and dyslipidemia were early-onset reversible risk factors of AMI in both areas. The ranking of impacts of them on the age from high to low was obesity (β = -6.7), smoking (β = -6.1), and dyslipidemia (β = -4.8) in the urban areas, while it was smoking (β = -8.5), obesity (β= -7.8), and dyslipidemia (β = -5.1) in the rural areas. Furthermore, the average onset ages for the patients who smoke, are obese, and have dyslipidemia simultaneously was significantly earlier than for patients with none of these comorbidities in both urban (13.6 years) and rural (14.9 years) areas. The findings of this study suggest that the different prevention strategies for AMI should be implemented in urban and rural areas.
这项横断面研究旨在调查中国台湾东部城乡地区急性心肌梗死（AMI）发病年龄风险因素排名的差异。研究数据来自2000年1月至2015年12月首次发作的AMI患者，其中城市地区有1060例，农村地区有953例，数据包括发病年龄以及传统风险因素，如性别、吸烟、糖尿病、高血压、血脂异常和体重指数（BMI）。多元线性回归分析结果显示，吸烟、肥胖和血脂异常是两个地区AMI的早发可逆风险因素。在城市地区，它们对发病年龄影响的排名从高到低依次为肥胖（β = -6.7）、吸烟（β = -6.1）和血脂异常（β = -4.8）；而在农村地区则是吸烟（β = -8.5）、肥胖（β = -7.8）和血脂异常（β = -5.1）。此外，在城市（13.6岁）和农村（14.9岁）地区，同时吸烟、肥胖和患有血脂异常的患者的平均发病年龄明显早于无这些合并症的患者。本研究结果表明，城乡地区应实施不同的AMI预防策略。
